M.B.B.S. [2nd Prof.]
BF/2020/06
Pharmacology - B
M.M. : 40
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Time : 3 HoursNote: 1.
Attempt all questions. Illustrate your answer with suitable diagrams.
2.
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ATTEMPT BOTH PARTS IN SINGLE ANSWER BOOK ONLY.3.
NO SUPPLEMENTARY SHEET SHALL BE ALLOWED/PROVIDED
4.
The student must write Q.P. Code in the space provided on the Title
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page of the Answer Book.PART - I
1.
Explain why?
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a.Propranolol is used in the treatment of thyrotoxicosis.
[2]
b.
Artemisinin derivatives are preferably prescribed in combinations for
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treatment of malaria.[2]
c.
LMW heparin is preferred over conventional heparin in treatment of deep
vein thrombosis.
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[2]d.
Estrogen is combined with progesterone for contraception in female.
[2]
2.
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Enumerate insulin preparations. Describe mechanism of action, pharmacologicalactions of lispro insulin.
[2+2+2]
3.
Discuss the rationale for the use of:
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a.Leflunomide in the treatment of rheumatoid arthritis.
[2]
b.
tissue-Plasminogen activator in the treatment of myocardial infarction.
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[2]c.
Bisphosphonates in the treatment of osteoporosis.
[2]
d.
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Letrozol in the treatment of breast cancer.[2]
PART ? II
4.
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Discuss the pharmacotherapy of the following:-a.
H. pylori induced peptic ulcer.
[2]
b.
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Pulmonary tuberculosis.[2]
c.
Acute attack of angina
[2]
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5.Discuss the therapeutic uses and adverse effects of:-
a.
Prednisolone
[2]
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b.Rifampicin
[2]
c.
Bisoprolol
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[2]6.
Write short notes on:-
a.
Penicillamine
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[2]b.
PUVA therapy
[2]
c.
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Albendazole[2]
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