Q.P. Code: MBN205
M.B.B.S. 2nd Prof.
(New Scheme w.e.f. 2019 admission onwards)
BF/2023/06
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Microbiology ? AM.M. : 100
Time : 3 Hours(First 30 Min. for MCQs)
Note: 1.
Use OMR Sheet to answer Multiple Choice Questions(MCQs).
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2.Attempt all questions. Illustrate your answers with suitable diagrams
3.
NO SUPPLEMENTARY SHEET SHALL BE ALLOWED/PROVIDED
4.
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The student must write Q.P. Code in the space provided on OMR Sheet and the Title page ofthe Answer Book.
Q.1
MCQs (Attempt on OMR sheet)
[1x20]
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1.Most antigenic component in a microbe is
a.
Lipid
b.
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Proteinc.
Carbohydrate
d.
Glycolipid
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2.Which immunoglobin has the least concentration in the human body?
a.
IgG
b.
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IgMc.
IgA
d.
IgE
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3.VDRL test is based on
a.
Precipitation reaction
b.
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Agglutination reactionc.
ELISA
d.
CFT
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4.What is the percentage of agar in most solid media?
a.
0.2%
b.
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2%c.
4%
d.
6%
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5.Following is an example of enrichment medium
a.
Alkaline peptone water
b.
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Chocolate agarc.
Blood agar
d.
Nutrient agar
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6.Concentration of glutaraldyhyde used in high level disinfection of endoscopes is
a.
0.5%
b.
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1%c.
1.5%
d.
2%
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7.PCR is used to
a.
Detect target plasmids
b.
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Amplify small amount of DNAc.
Seal the cut ends of DNA
d.
Cleave the bacterial plasmid
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8.Antibiotic sensitivity testing is done on
a.
Blood agar
b.
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MacConkey agarc.
Chocolate agar
d.
Mueller Hinton agar
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9.Horizontal transfer of `R' factor is by
a.
Transduction
b.
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Transformationc.
Conjugation
d.
Fusion
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10.Superantigen is produced by
a.
Staphylococcus aureus
b.
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Streptococcus pneumoniac.
Pseudomonas
d.
Clostridium
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Page 1 of 311.
A 15 year old girl had splenomegaly, leucopenia, fever and died in a few days. Longitudinal ulcers
were found in the intestine. What could be the probable diagnosis?
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a.Typhoid
b.
Tuberculosis
c.
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Amoebiasisd.
PUO
12.
True about B. recurrentis is
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a.Causes leptospirosis
b.
Water born disease
c.
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Transmitted by loused.
Transmitted by flea
13.
Weil's disease is caused by
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a.Leptospira
b.
Proteus
c.
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Yersiniad.
Borrelia
14.
Antibody dependent enhancement is a feature of
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a.Dengue hemorrhagic fever
b.
SSPE
c.
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SSSSd.
Enteric fever
15.
Cerebral malaria is caused by
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a.P.falciparum
b.
P.vivax
c.
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P.ovaled.
P.malariae
16.
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Traveler's diarrhea is caused bya.
ETEC
b.
EHEC
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c.EPEC
d.
EIEC
17.
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A stool examination was carried which showed organism with darting motility. Which of the followingmay be present in stool?
a.
V.cholerae
b.
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Shigellac.
Salmonella
d.
E.coli
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18.Space vehicle virus is
a.
Reovirus
b.
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Retrovirusc.
Rhabdovirus
d.
Adenovirus
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19.Largest protozoan is
a.
E.histolytica
b.
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B.colic.
E.coli
d.
P.vivax
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20.If the sample of a patient is HIV positive. The report can be given to
a.
Patient himself
b.
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His spousec.
His relative
d.
anyone
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Page 2 of 3Q.2.
A 10 year old girl gets severe bronchial asthma attacks every year in the month of April. She stays
close to a large garden, which has plenty of flowering trees.
a.
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What is the likely cause of her respiratory disorder?b.
Describe the pathogenesis of the above disorder.
c.
Enumerate a specific test to make a definitive diagnosis in the above case.
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d.What is the treatment approach of the above case?
[2+4+2+4]
Q.3.
Write short notes on:-
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[5x4]a.
IgA
b.
Koch's postulates
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c.Bleaching powder
d.
R-Plasmid
Q.4.
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Explain in short:-[3x5]
a.
Indirect immunofluorescence test
b.
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Catalase testc.
Real time PCR
d.
Differences between amebic and bacillary dysentery
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e.Plasmodium LDH test
Q.5.
Short answers (applied aspects):-
[6x3]
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a.Enterotoxigenic E. coli
b.
Hepatitis B vaccine
c.
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Lab diagnosis of enteric feverQ.6.
Write in brief about:-
[5x3]
a.
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Strategy III in HIV testingb.
Pathogenicity of ascariasis
c.
A positive report of HIV is given to a client without counseling. Explain the lapse.
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