Download BFUHS MBBS 2nd Year MBN205 Microbiology A Feb 2022 mcq Question Paper

Total No. = 03 pages
Q.P. Code: MBN205
M.B.B.S. 2nd Prof.
(New Scheme w.e.f. 2019 admission onwards)
BF/2022/02

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Microbiology ? A
M.M. : 100
Time : 3 Hours(First 30 Min. for MCQs)
Note: 1.
Use OMR Sheet to answer Multiple Choice Questions(MCQs).

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2.
Attempt all questions. Illustrate your answers with suitable diagrams
3.
NO SUPPLEMENTARY SHEET SHALL BE ALLOWED/PROVIDED
4.

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The student must write Q.P. Code in the space provided on OMR Sheet and the Title page of
the Answer Book.
Q.1
MCQs (Attempt on OMR sheet)
[1x20]

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1.
Man acquires malaria by bite of female anopheles mosquito. Which of the following is the infective
form of malarial parasite to man?
a.
Sporozotie

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b.
Gametocytes
c.
Trophozoite
d.

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Merozoites
2.
A 15 year old girl, gets severe bronchial asthma attacks every year in the month of March. She stays
close to a garden in New Delhi; which has plenty of flowering trees. What is the likely cause of her
respiratory problem?

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a.
atopic type 1 hypersensitivity disorder
b.
Type 2 hypersensitivity disorder
c.

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Type 3 hypersensitivity disorder
d.
Type 4 hypersensitivity disorder
3.
A 55 year old man was admitted to a local hospital with fever and chills and had received multiple

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courses of antibiotics. Blood culture grew Gram positive cocci, which tested positive with group D
streptococcal antisera. The isolate was resistant to penicillin and vancomycin. Which of the following
is the most likely pathogen?
a.
Streptococcus pneumonia

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b.
Enterococcus faecium
c.
Streptococcus agalactiae
d.

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Streptococcus pyogenes
4.
A 35 year old truck driver had history of sexual contact with multiple partners. What is the relative risk
of transmission of HIV to him?
a.

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0.1 -1%
b.
2 - 20%
c.
30-50%

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d.
50-90 %
5.
In emergency of tertiary care hospital, a 15 yr male presented with tenesmus, abdominal pain, and
passage of bloody stools 7-8 times a day, for the past 2-3 days. What will be the presumptive

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etiological agent?
a.
Vibrio cholerae
b.
Shigella dysenteriae

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c.
Salmonella Typhi
d.
Enterotoxigenic Escherichia coli
6.

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A 50 year old executive, staying in a farmhouse; equipped with swimming pool reported with three
day history of high grade fever, headache, severe myalgias and diffuse rash on the trunk. Blood
examination revealed a TLC count of 2,000/mm3. Test for Dengue non-structural protein 1 (NSI) has
been positive in this case. The likely diagnosis of this case is
a.

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Dengue haemmorhagic fever
b.
Chickungunya infection
c.
measles

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d.
Yellow fever.
7.
A 20 yr female reported to the emergency department with the complaints of severe watery diarrhoea
(10- 15 times) and vomiting for 1 day. Stool sent for examination has rice water type of appearance .

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Probable etiological organism in this patient is:
a.
Staphylococcus aureus
b.
Bacillus cereus

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c.
Vibrio cholerae
d.
Salmonella typhi
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8.
Few students of college reported to medical officer incharge with the complaints of nausea, vomiting
and diarrhoea after eating fried rice and manchurian in a mess. All the students reported to the doctor
within 1-6 hours after having lunch. What would be the probable causative organism?

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a.
Bacillus cereus
b.
Staphylococcus aureus
c.

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Shigella dysenteriae
d.
Salmonella Typhi
9.
A 36 years male from Rewa, M.P. presented with fever, generalized weakness and breathlessness. His

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chest X-ray revealed bilateral diffuse infiltrates. Ultrasound of abdomen revealed hepatosplenomegaly
and lymphadenopathy. Fungal culture of bone marrow aspirate (BMA) revealed septate hyphae with
tuberculate macroconidia 10?m in diameter. The likely diagnosis is
a.
Disseminated histoplasmosis

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b.
Disseminated Blastomycosis
c.
Candidiasis
d.

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Aspergillosis
10.
A 35-year-old man comes to the emergency department complaining of high fever, chills, severe
headache, and confusion. He has recently returned from Africa. A peripheral blood smear reveals
multiple ring structures and crescent-shaped gametes. Which of the following organisms is the most

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likely cause?
a.
Plasmodium malariae
b.
Plasmodium vivax

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c.
Leishmania species
d.
Plasmodium falciparum
11.

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A 40 year old female was hospitalized on account of fever, anorexia abdominal pain episodes of
loose stools with blood for 8 days. Examination of the stool revealed large motile trophozoites
(approximately 60 ?m length). The likely diagnosis is
a.
Balantidium coli infection

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b.
Amebic infection
c.
Cryptosporidium infection
d.

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Giardia infection
12.
A 30 year old male presented to Skin/VD OPD with chief complaint of penile chancre. He gave
history of unprotected sexual intercourse with commercial sex workers. The consulted advised VDRL
test. VDRL test is based on:-

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a.
Precipitation reaction
b.
Agglutination reaction
c.

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ELISA
d.
Complement fixation Test
13.
A 10 year malnourished child from village presented with history of loss of appetite, weight loss,

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diarrhoea, breathlessness, blood in stool and itchy rash. Peripheral blood smear examination reveals
hypochromic, microcytic anaemia. The most probable causative agent is
a.
Entamoeba histolytica
b.

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Giardia lambia
c.
Ancylostoma duodenales
d.
Ascaris lumbricoides

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14.
A 20 year old female admitted in the hospital with fever that was initially low and increased daily to
reach as high as 1040 F. She also had headache, abdominal discomfort for last 5 days. On examination
she was toxic with high grade fever. She had coated tongue. Her vital signs were normal. What is the
probable clinical diagnosis ?

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a.
Enteric fever
b.
Malaria
c.

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Dengue
d.
Brucellosis
15.
A thirty eight years female from Patna (Bihar) presented with fever of 5 weeks duration, progressive

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weakness and abdominal discomfort. Physical examination revealed, enlarged spleen 4cms below left
costal margin and associated hepatomegaly. Laboratory investigations revealed Hb level of 6.5
gm/dl.Bone marrow aspiration revealed 5?m ,round amasigote forms.The likely diagnosis is
a.
Visceral Leishmaniasis

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b.
Trypanosomiasis
c.
Toxoplasmosis
d.

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Disseminated amoebiasis
16.
A sixty five year old female complained of abdominal pain, flatulence and expulsion of small whitish
segments. Patient gives history of consuming raw meat. Stool examination revealed roundish 41?m
egg. The egg is likely to be of

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a.
Taenia
b.
Trichuris
c.

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H. nana
d.
D. latum
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17.

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A thirty one year old female presented with history of intense pruritus in perinal region. If a diagnosis
of Enterobiasis is to be supported ,then the eggs should be
a.
rounded
b.

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planoconvex
c.
barrel shaped
d.
operculated

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18.
After consumption of honey, an infant presents to the emergency department due to difficulty
breathing, constipation, and anorexia. Upon examination, the physician notes flaccid paralysis. A toxin
screen of the stool was done to identify causative the agent. What is the most probable causative
agent?

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a.
Staphylococcus aureus.
b.
Non typhoidal salmonella
c.

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Clostridium botulinum
d.
Vibrio parahaemolyticus
19.
A 40 year woman, presented with nausea, vomiting and pain in right upper quadrant. Her

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abdominal.examination revealed enlarged liver. Her hepatitis serologic tests profile revealed hepatitis
C antibody test positive.Hepatitis C belongs to
a.
Picornaviridae
b.

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Hepadnaviridae
c.
Flaviviridae
d.
Retroviridae

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20.
A 30 years man from Bulandshahr, UP presented with 3 week history of pain in right flank and
anorexia of 7 days duration. He gave history of loose motions of 8 days duration about 5 months back.
His physical examination revealed enlarged liver. CECT examination of abdomen revealed a solitary
cystic lesion in liver.Aspirate from the liver revealed about 20?m sized trophozoites.The case is likely

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to have
a.
Acanthamoeba infection
b.
E. histolytica infection

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c.
Leishmania infection
d.
Balantidium infection
Q.2. A 10 year old child reported to Emergency Medicine Block/ Department with history of watery

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diarrhea for last 1 ? days. Child, on examination is dehydrated. Gross examination of stool with
microscopy shows rice water stool with presence of bacteria showing darting motility suggestive of
vibrio cholera.
[4+4+2+2]
a.

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Enumerate steps on laboratory diagnosis of cholera.
b.
Write about pathogenesis of cholera.
c.
Enumerate steps in management of cholera.

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d.
List two methods of prevention of diarrhea at community level.
Q.3. Write short notes on:-
[5x4]
a.

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Differences in active and passive immunity.
b.
Differences between endotoxin and exotoxin
c.
Differences between gram positive and gram negative bacterial cell wall

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d.
Principle of autoclave and list four articles that are routinely autoclaved in microbiology
laboratory.
Q.4. Explain in short:-
[3x5]

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a.
Mechanism of acute anaphylaxis
b.
Causes, clinical presentation and management of food borne diarrhea
c.

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By diagram only- Serological markers of Hepatitis B
d.
Applications of ELISA
e.
Interpretation of widal test in diagnosis of enteric fever

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Q.5. Short answers (applied aspects):-
[6x3]
a.
Laboratory diagnosis of dengue virus infection
b.

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Acute amoebic dysentery
c.
Anaerobic culture thechniques
Q.6. Write in brief about:-
[5x3]

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a.
Father of Microbiology
b.
Transduction in bacteria
c.

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Attitude in practice while disclosing positive reports to highly sick patients or their relatives
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