Download BFUHS MBBS 2nd Year MBN206 Microbiology B Nov 2022 mcq Question Paper

Total No. = 03 pages
Q.P. Code: MBN206
M.B.B.S. 2nd Prof.
(New Scheme w.e.f. 2019 admission onwards)
BF/2022/06

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Microbiology ? B

M.M. : 100
Time : 3 Hours(First 30 Min. for MCQs)
Note: 1.

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Use OMR Sheet to answer Multiple Choice Questions(MCQs).
2.
Attempt all questions. Illustrate your answers with suitable diagrams
3.
NO SUPPLEMENTARY SHEET SHALL BE ALLOWED/PROVIDED

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4.
The student must write Q.P. Code in the space provided on OMR Sheet and the Title page of
the Answer Book.
Q.1
MCQs (Attempt on OMR sheet)

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[1x20]
Tick the most appropriate answer:
1.
An 5 year old child with high grade fever, throat pain and inability to swallow was brought to the
emergency. On oral examination, white patches were found on the tonsillar fauces which bled on

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touch. The clinical diagnosis of diptheria was made and throat swab was sent to the microbiology
laboratory for etiological confirmation. The metachromatic granules of Corynebacterium diptheriae
can be stained by which special stain:
a.
Ziehl neelsen stain

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b.
Albert stain
c.
Gram stain
d.

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Leishman stain
2.
A 4 year old refugee boy presented with fever, cough and dyspnoea for the past 5 days. Sputum culture
examination revealed colonies near the S. aureus streak line on blood agar. What will be your
etiological diagnosis?

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a.
Pneumococcous
b.
Moraxella catarrhalis
c.

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Hemophilus influenza
d.
Bacillus anthracis
3.
A young rural patient presented with papules and ulcers on his body. He gave a history of frequently

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swimming in his local pond. On examination, a minor cut was observed on his left leg. What could be
the most likely cause of his cutaneous infection?
a.
Cutaneous anthrax
b.

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cutaneous diptheria
c.
M. marinum
d.
M. chelonae.

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4.
A 5-year-old child develops a low-grade fever, coryza, conjunctivitis, and Koplik spots. The physician
can conclude that:
a.
The child has probably not been successfully vaccinated with the MMR vaccine.

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b.
The child's pregnant mother is at risk of becoming infected and her unborn child developing
congenital abnormalities, including mental retardation.
c.
A rash will soon develop on the child's face and will last only 2?3 days.

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d.
Treatment of the child with the antiviral drug ribavirin should be initiated immediately to
minimize the chance of development of acute encephalitis.
5.
A 50 year old patient (without wearing a mask) presented with complaints of dry cough, fever and sore

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throat along with chest pain and hemoptysis. His throat swab was sent which tested positive for
COVID-19. Chest Xray was done which revealed lobar consolidation. What could be the possible
etiological diagnosis of this superadded infection?
a.
Aspergillus

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b.
Trichophyton
c.
Mucor
d.

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Penicillium
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6.
Neisseria gonorrhoea is leading causes of STDs. Females affected by Neisseria gonorrhoeae usually
remain asymptomatic. Which of the following is the best site to obtain a swab in asymptomatic

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gonorrhea?
a.
Endocervix
b.
Urethra

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c.
Lateral vaginal wall
d.
Posterior fornix
7.

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A young male had unprotected intercourse with a commercial sex worker. 2 weeks later, he developed
painless indurated ulcer on his glans penis that exuded clear serum on pressure. Bilateral inguinal
lymph nodes were enlarged but not tender. The most appropriate diagnostic test is:
a.
Western blot for HIV

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b.
Gram staining of ulcer discharge
c.
Leishman stain of lymph node aspirate
d.

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Dark field microscopy of ulcer discharge.
8.
A 30 year old female came with multiple painful tiny vesicular ulcers on vulvaand vaginal walls. On
examination, there was painful enlarged lymph nodes. The causative organism might be:
a.

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C. granulomatis
b.
HSV-2
c.
H. ducreyi

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d.
HSV-1
9.
Plague is transmitted by:
a.

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Cat flea
b.
Soft tick
c.
X. cheopsis

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d.
Louse
10.
A 25 year old patient presented with features of acute meningoencephalitis. Her CSF examination
revealed motile unicellular microorganisms. The most likely organism is:

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a.
Trypanosoma cruzi
b.
Neisseria meningitidis
c.

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Cryptococcous neoformans d.
Naegleria fowleri
11.
The most common organism amongst the following that causes acute meningitis in an AIDS patient:
a.

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Neisseria meningitides
b.
Cryptococcous neoformans
c.
Streptococcous agalactiae

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d.
Listeria monocytogenes
12.
A diabetic patient suffers from a soft tissue infection, microbiological examination of which reveals
broad ribbon shaped aseptate hyaline hyphae. Which fungus is the likely responsible for this infection:

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a.
Candida
b.
Mucor
c.

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Penicillium
d.
Aspergillus
13.
An HIV +ve immunocompromised patient presented with symptoms of difficulty in vision and

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photophobia. On ocular examination, the physician observed features of chorioretinitis. Which parasite
is likely responsible for this infection:
a.
Acanthamoeba
b.

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Toxoplasma
c.
Plasmodium
d.
Entamoeba

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14.
Multidrug therapy is given for tuberculosis because:
a.
To decrease toxicity
b.

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To widen antimicrobial spectrum
c.
To delay development of resistance
d.
To prevent toxin release by the pathogen.

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15.
A pleural fluid sample from pulmonary medicine ward is received in the microbiology laboratory for
ZN staining. On smear examination, acid fast bacilli were observed. All of these can be the likely
pathogen except:
a.

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Nocardia
b.
M. tuberculosis
c.
NTM

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d.
Actinomycetes
16.
A 70 year old male patient presented to emergency with high grade fever, chest pain, increased
respiratory rate and cough with expectoration. His sputum was sent to the lab for gram staining which

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showed presence of pus cells and Gram positive cocci in pairs. Which of the following will help in
confirming the diagnosis?
a.
Coagulase test
b.

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Catalase test
c.
Bile solubility
d.
Bacitracin sensitivity

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17.
Dermatophytosis is superficial mycoses affecting skin,hair and nail . Which of the following

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dermatophyte infects skin and hair only?
a.
Trichophyton rubrum
b.
Microsporum spp

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c.
Epidermophyton spp
d.
Trichophyton mentagrophytes
18.

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A 8 month old infant with history of incomplete childhood vaccination presented with bouts of
spasmodic cough with cyanosis and a typical inspiratory whoop. What is the most appropriate
diagnosis?
a.
Tuberculosis

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b.
Interstitial pneumonia
c.
Pertussis
d.

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Pharyngitis
19.
Mycetoma is chronic slowly progressive granulomatous infection of skin and subcutaneous tissue.
Which of the following triad is manifestation of Mycetoma?
A. Swelling, discharging sinuses, presence of granules

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B. Swelling, nodule formation, lymphadenopathy
C.Lymphadenopathy, ulcerative lesions, osteoarthritis
D. Swelling, erythema, nodulo-ulcerative lesions
20.
A patient presented with headache and projectile vomiting along with alteration in sensorium. India

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ink staining shows a capsulated organism. Which of the following is the most likely diagnosis?
a.
Cryptococcus
b.
Blastomyces

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c.
Histoplasma
d.
Coccidiodes
Q.2. A 35 year old truck driver has been brought to the emergency ward with history of bouts of acute

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diarrhea, weight loss and fever for the last three months. On examination there was diminished breath
sound on both sides of the chest. Chest X-ray revealed consolidation of both lungs. There was
generalized lymphadenopathy.
[4x3]
a.

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Define opportunistic infections
b.
What are the possible etiological agents of opportunistic infections in this individual
c.
Discuss the pathogenesis of opportunistic infections

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Q.3. Describe briefly:
[5x4]
a.
Name the clostridium tetani toxins and mechanism of action
b.

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Classification of mycobacterium
c.
Define acute bacterial neonatal meningitis. Discuss the aetiological agents
d.
Discuss the aetiologial agents chronic meningitis and laboratory diagnosis

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Q.4. Write briefly: -
[3x5]
a.
Herpes virus infections
b.

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Serological diagnosis of syphilis
c.
Primary amebic meningoencephalitis
d.
Candidal infections

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e.
Cerebral malaria
Q.5. Discuss briefly: -
[6x3]
a.

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Laptospirosis and its diagnosis
b.
Mention the microbial pathogens causing congenital infections. Discuss the laboratory
diagnosis.
c.

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Biological waste disposal methods
Q.6. Write short notes: -
[5x3]
a.
Laboratory diagnosis of leprosy

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b.
Prevention of hospital acquired infections
c.
Confidentiality in microbiology reports
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