Madhya Pradesh Medical Science University,
Jabalpur
MBBS Second Professional Examination April-
2024
Subject- Pharmacology
Maximum Marks :100
Time: 3:00 Hours
Instructions:
a) All questions are compulsory
c) Answers of Questions and Sub-questions must be
written strictly according to serial order of question
paper.
d) MCQ has to be answered in theory answer book
with black or blue pen in brackets; for example: - 1.
(a) 2. (c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
counted in marks and action will be taken according to
UFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
Q1. Total MCQs: 10 10 x 1 = 10
1. Which of the following drug is approved by FDA for
generalized HSDD (Hypoactive sexual disorder in
premenopausal women):
Clomiphene
2. All of the following drugs are used for treating alcohol
use disorder (AUD), EXCEPT:
(a) Disulfiram (b) Naltrexone (c) Fomepizole (d)
3. Which of the following is the most common
paradoxical side effect of Indomethacin:
(a) Hypersensitivity (b) Peptic ulcer (c) Frontal
headache (d) Nephropathy
Toxoplasmosis during early pregnancy:
(a) Spiramycin (b) Clindamycin (c) Sulfadiazine (d)
Pyrimethamine
5. Which of the following drugs is used for treatment of
(a) Mebendazole (b) Metronidazole (c) Albendazole (d)
Tinidazole
6. Which of following antiviral is used for the treatment
of corona virus:
Remdesivir
7. All of the following drugs inhibit the peripheral
conversion of T4 to T3, EXCEPT:
(a) Methimazole (b) Propylthiouracil (c) Propranolol (d)
8. All of the following drugs are used in the treatment of
osteoporosis, EXCEPT:
(a) Bisphosphonate (b) Raloxifine (c) Tamoxifen (d)
Calcitonin
cross reactivity with Aztreonam:
(a) Ceftazidime (b) Ceftaroline (c) Ceftriaxone (d)
Cefotaxime
10. Which of the following drug is effective in both grand
(a) Phenobarbitone (b) Sodium valproate (c) Phenytoin
(d) Carbamazepine
Q2. Long Answer Questions 2 x 20 = 40
a. A 30-year-old mother comes to OPD. On history
to space out her next child and consulting you for taking
contraceptive pills.
I Which type of hormonal contraceptive would you
suggest?
oral contraceptive pills.
III Write regimens used as Emergency contraceptives.
IV Write basis used of clomiphene in infertility.
b. A 47-year-old man attends neurology clinic with
moves slowly and has diminished range of facial
expressions. His speech is slow and monotonous. He is
diagnosed to be suffering from early stage of Parkinson's
disease. He was prescribed levodopa/Carbidopa
I Explain the rationale of combining levodopa with
carbidopa and what are the advantages of combination.
II Classify Antiparkinsonian drugs.
III What are advantages of dopamine receptor agonists
IV Enumerate drugs causing Parkinsonism and write
treatment of drug-induced Parkinsonism.
Q3. Brief Answer Questions 6 x 05 = 30
a. Enumerate 3rd generation Cephalosporins & write
b. Enumerate Atypical antipsychotics. Write their
advantages over typical antipsychotics.
c. Enumerate nonsteroidal anti-inflammatory drugs
(NSAID). Write basis of use of Paracetamol as antipyretic.
e. Enumerate SSRIs & write rationale for use of
Fluoxetine in depression.
f. Enumerate drugs for MDR & XDR tuberculosis. Write
basis of combination therapy in tuberculosis.
Q4. Short Answer Questions 10 x 2 = 20
a. Explain oxytocin is preferred over ergometrine for
induction of labour.
b. Abrupt withdrawal of glucocorticoids after prolonged
therapy is not advised, why?
d. Write drug used in anaerobic infection.
e. Write drug used is Staphylococcal infection.
f. Explain Lugol's iodine is used prior to thyroid surgery.
g. Write drugs for chloroquine resistant P. falciparum
h. Write notes on fluoroquinolones.
i. Write basis of use of valproate in epilepsy.
j. Why morphine is contraindicated in patients having
head injury.
Jabalpur
MBBS Second Professional Examination April-
2024
Subject- Pharmacology
--- Content provided by FirstRanker.com ---
Paper- II (new scheme)Maximum Marks :100
Time: 3:00 Hours
Instructions:
a) All questions are compulsory
--- Content provided by FirstRanker.com ---
b) Draw diagrams wherever necessaryc) Answers of Questions and Sub-questions must be
written strictly according to serial order of question
paper.
d) MCQ has to be answered in theory answer book
--- Content provided by FirstRanker.com ---
e) Please write MCQ answer neatly and in serial orderwith black or blue pen in brackets; for example: - 1.
(a) 2. (c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
--- Content provided by FirstRanker.com ---
considered as malpractice, such answers will not becounted in marks and action will be taken according to
UFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
--- Content provided by FirstRanker.com ---
marks should answered in up to 60 marks.Q1. Total MCQs: 10 10 x 1 = 10
1. Which of the following drug is approved by FDA for
generalized HSDD (Hypoactive sexual disorder in
premenopausal women):
--- Content provided by FirstRanker.com ---
(a) Flibanserin (b) Mifepristone (c) Finasteride (d)Clomiphene
2. All of the following drugs are used for treating alcohol
use disorder (AUD), EXCEPT:
(a) Disulfiram (b) Naltrexone (c) Fomepizole (d)
--- Content provided by FirstRanker.com ---
Acamprostate3. Which of the following is the most common
paradoxical side effect of Indomethacin:
(a) Hypersensitivity (b) Peptic ulcer (c) Frontal
headache (d) Nephropathy
--- Content provided by FirstRanker.com ---
4. Which of the following drug used for AcuteToxoplasmosis during early pregnancy:
(a) Spiramycin (b) Clindamycin (c) Sulfadiazine (d)
Pyrimethamine
5. Which of the following drugs is used for treatment of
--- Content provided by FirstRanker.com ---
Neurocysticercosis:(a) Mebendazole (b) Metronidazole (c) Albendazole (d)
Tinidazole
6. Which of following antiviral is used for the treatment
of corona virus:
--- Content provided by FirstRanker.com ---
(a) Cidofovir (b) Ganciclovir (c) Amantadine (d)Remdesivir
7. All of the following drugs inhibit the peripheral
conversion of T4 to T3, EXCEPT:
(a) Methimazole (b) Propylthiouracil (c) Propranolol (d)
--- Content provided by FirstRanker.com ---
Dexamethasone8. All of the following drugs are used in the treatment of
osteoporosis, EXCEPT:
(a) Bisphosphonate (b) Raloxifine (c) Tamoxifen (d)
Calcitonin
--- Content provided by FirstRanker.com ---
9. Which of the following Cephalosporins has allergiccross reactivity with Aztreonam:
(a) Ceftazidime (b) Ceftaroline (c) Ceftriaxone (d)
Cefotaxime
10. Which of the following drug is effective in both grand
--- Content provided by FirstRanker.com ---
mal and petit mal epilepsy:(a) Phenobarbitone (b) Sodium valproate (c) Phenytoin
(d) Carbamazepine
Q2. Long Answer Questions 2 x 20 = 40
a. A 30-year-old mother comes to OPD. On history
--- Content provided by FirstRanker.com ---
taking, she had 4 months baby and lactating. She wantedto space out her next child and consulting you for taking
contraceptive pills.
I Which type of hormonal contraceptive would you
suggest?
--- Content provided by FirstRanker.com ---
II Enumerate Adverse effect and Contraindication oforal contraceptive pills.
III Write regimens used as Emergency contraceptives.
IV Write basis used of clomiphene in infertility.
b. A 47-year-old man attends neurology clinic with
--- Content provided by FirstRanker.com ---
complaints of resting tremors of right hand and arm. Hemoves slowly and has diminished range of facial
expressions. His speech is slow and monotonous. He is
diagnosed to be suffering from early stage of Parkinson's
disease. He was prescribed levodopa/Carbidopa
--- Content provided by FirstRanker.com ---
250mg/25mg four times daily.I Explain the rationale of combining levodopa with
carbidopa and what are the advantages of combination.
II Classify Antiparkinsonian drugs.
III What are advantages of dopamine receptor agonists
--- Content provided by FirstRanker.com ---
over levodopa/carbidopa combination.IV Enumerate drugs causing Parkinsonism and write
treatment of drug-induced Parkinsonism.
Q3. Brief Answer Questions 6 x 05 = 30
a. Enumerate 3rd generation Cephalosporins & write
--- Content provided by FirstRanker.com ---
their therapeutic uses and adverse effects.b. Enumerate Atypical antipsychotics. Write their
advantages over typical antipsychotics.
c. Enumerate nonsteroidal anti-inflammatory drugs
(NSAID). Write basis of use of Paracetamol as antipyretic.
--- Content provided by FirstRanker.com ---
d. Write notes on SGLT-2 inhibitors.e. Enumerate SSRIs & write rationale for use of
Fluoxetine in depression.
f. Enumerate drugs for MDR & XDR tuberculosis. Write
basis of combination therapy in tuberculosis.
--- Content provided by FirstRanker.com ---
Q4. Short Answer Questions 10 x 2 = 20
a. Explain oxytocin is preferred over ergometrine for
induction of labour.
b. Abrupt withdrawal of glucocorticoids after prolonged
therapy is not advised, why?
--- Content provided by FirstRanker.com ---
c. Enumerate 04 drugs used in prophylaxis of migraine.d. Write drug used in anaerobic infection.
e. Write drug used is Staphylococcal infection.
f. Explain Lugol's iodine is used prior to thyroid surgery.
g. Write drugs for chloroquine resistant P. falciparum
--- Content provided by FirstRanker.com ---
malaria.h. Write notes on fluoroquinolones.
i. Write basis of use of valproate in epilepsy.
j. Why morphine is contraindicated in patients having
head injury.
--- Content provided by FirstRanker.com ---
***