Jabalpur
MBBS Second Professional Examination June-
2023
Subject- Pharmacology
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Paper- II (old scheme)Time: 3:00 Hours
Maximum Marks: 40
Instructions:
a) All questions are compulsory
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b) Draw diagrams wherever necessaryc) Answers of Questions and Sub-questions must be
written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
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with black or blue pen in brackets; for example: - 1. (a) 2.(c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
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counted in marks and action will be taken according toUFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 words.
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Q1. Total MCQs: 1616 x 1/2 = 8
1. Fourth Generation cephalosporin is
(a) Cefepime
(b) Cefprozil
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(c) Cefixime(d) Cefadroxil
2. Antagonist of Benzodiazepine is
(a) Naltrexone
(b) Flumazenil
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(c) Naloxone(d) N-Acetyl-cysteine
3. Which of the following drug can decrease the size of
prostate
(a) Prazosin
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(b) Sildenafil(c) Finasteride
(d) Testosterone
4. Cryptococcal Meningitis is treated with
(a) Griseofulvin
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(b) Amphotericin B(c) Posaconazole
(d) Caspofungin
5. Dissociative anesthesia is seen on administration of:
(a) Ether
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(b) Halothane(c) Enflurane
(d) Ketamine
6. Which of the following drug is a SERM useful for
treatment of osteoporosis?
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(a) Raloxifene(c) Letrozole
(b) Bisphosphonate
(d) Calcitonin
7. Drug of choice for prophylaxis of Mania is:
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(a) Clozapine(b) Haloperidol
(c) Lithium
(d) Diazepam
8. Total dose of chloroquine (250 mg Tablet) in Vivax
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malaria is:(a) 4
(b) 6
(c) 8
(d) 10
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9. Tramadol is(a) Anti-flatulent
(b) Anti-reflux drug
(c) Beta-Blocker
(d) Opioid analgesic
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10. Drug used as aversion therapy in Alcohol
dependence is:
(a) Disulfiram
(b) Diazepam
(c) Propranolol
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(d) Methadone11. Which neurotransmitter system is primarily targeted
by tricyclic antidepressants (TCAS)?
(a) Dopamine
(b) Serotonin
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(c) GABA(d) Norepinephrine
12. Which of the following analgesic drugs is a
selective cyclooxygenase-2 (COX-2) inhibitor?
(a) Ibuprofen
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(b) Acetaminophen(c) Celecoxib
(d) Morphine
13. Which of the following medications used in the
treatment of gout works by increasing renal excretion of
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uric acid?(a) Colchicine
(b) Allopurinol
(c) Febuxostat
(d) Probenecid
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14. Which of the following medications is a
glucocorticoid receptor antagonist used for the
treatment of Cushing's syndrome?
(a) Insulin lispro
(b) Metoprolol
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(c) Mifepristone(d) Pioglitazone
15. Which of the following drugs is a nitroimidazole
that is commonly used for the treatment of
trichomoniasis and giardiasis?
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(a) Chloroquine(b) Metronidazole
(c) Atovaquone
(d) Mefloquine
16. Which storage temperatures is recommended for
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maintaining the stability and potency of most vaccines?(a) -20?C (-4?F)
(c) 15-25?C (59-77?F)
(d) 37?C (98.6?F)
(b) 2-8?C (36-46?F)
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Q2. Long Answer Questions 2 x 5 = 10a. Classify Antiepileptic drugs based on their
Mechanism of Action. Write Uses and Adverse Effects
of Phenytoin.
b. Classify first- and second-line drugs for tuberculosis.
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Describe and discuss all anti-tuberculosis drugregimens recommended by RNTCP (2016).
Q3. Brief Answer Questions 4 x 3 = 12
a. Write the advantages of Atypical Antipsychotics over
Typical Antipsychotics.
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b. Explain the pharmacological actions and therapeuticactions of aspirin at its different doses.
c. Explain the differences in the mechanisms of action
between combined oral contraceptives (COCs) and
progestin-only contraceptives (POCs) in detail,
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including their effects on ovulation, cervical mucus, andendometrium.
d. Enumerate contraindications of corticosteroids.
Discuss the adverse effects associated with long-term
glucocorticoid therapy and strategies to minimize these
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effects.Q4. Short Answer Questions 10 x 1 = 10
a. Name Two Antipseudomonal Penicillins.
b. Name Two drugs of different classes used in Open
Angle Glaucoma.
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c. Write Two Contraindications of Morphine.d. Enumerate drugs used in treatment of Thyroid Storm.
e. Name two drugs used as Local Anaesthetics.
f. Enumerate pre-anaesthetic medications with their
role.
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g. Explain the mechanisms of bacterial resistance tobeta-lactam antibiotics.
h. Enumerate the adverse effects and contraindications
of lignocaine and adrenaline combination.
i. Enumerate shared toxicity of aminoglycoside
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antimicrobials.j. Enumerate the advantages of combining levodopa and
carbidopa.
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