Jabalpur
MBBS First Professional Examination Dec-2022
Subject- Biochemistry
Paper- II
--- Content provided by FirstRanker.com ---
Time: 3:00 HoursMaximum Marks :100
Instructions:
) All questions are compulsory
b) Draw diagrams wherever necessary
--- Content provided by FirstRanker.com ---
c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
--- Content provided by FirstRanker.com ---
(c)f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
--- Content provided by FirstRanker.com ---
UFM rules of university.g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 10
--- Content provided by FirstRanker.com ---
10 x 1 = 101. Opalescent urine is seen in
(a) Porphyria
(b) Alkaptonuria
(c) Chyluria
--- Content provided by FirstRanker.com ---
(d) Creatinuria2. The end product of catabolism of heme is
(a) Bile salt
(b) Bile acid
(c) Bile pigment
--- Content provided by FirstRanker.com ---
(d) Uric acid3. The flow of Genetic information from DNA to RNA to
Protein in living cells is
(a) Central dogma
(b) Replication
--- Content provided by FirstRanker.com ---
(c) Transcription(d) Reverse transcription
4. DNA Replication in Eukaryotes is
(a) Conservative
(b) Semi Conservative
--- Content provided by FirstRanker.com ---
(c) Dispersive(d) None of these
5. In Lac operon we see-
(a) 1 Regulatory Gene & 1 P site
(b) 1 Regulatory Gene, 1 Promoter site & 1 Operator
--- Content provided by FirstRanker.com ---
(c) 1 Regulatory Gene, 1 Promoter site, 1 Operator & 3Structural genes
(d) 2 Regulatory Gene, I Operator & 3 Structural genes
6. UAA, UAG & UGA are
(a) Initiating codons
--- Content provided by FirstRanker.com ---
(b) codons for lysine(c) codons for arginine
(d) Nonsense codons
7. The normal Serum Uric acid is-
(a) 8-10 mg%
--- Content provided by FirstRanker.com ---
(b) 4-7 mg%(c) 1-3 mg%
(d) 2-4 mg%
8. The purification of enzymes is mostly done by
(a) affinity chromatography
--- Content provided by FirstRanker.com ---
(b) ion exchange chromatography(c) paper chromatography
(d) none of these
9. Which of the vitamins listed has NO anti-oxidant
property?
--- Content provided by FirstRanker.com ---
(a) Vitamin C(b) Vitamin E
(c) Vitamin A
(d) Vitamin K
10. Which has no role in calculating calorie
--- Content provided by FirstRanker.com ---
requirements?(a) Respiratory quotient
(b) Specific Dynamic Action
(c) Nature of work
(d) Basal metabolic rate
--- Content provided by FirstRanker.com ---
Q2. Long Answer Questions
2 x 20 = 40
a. How heme is synthesized in body. Add a note on
various Porphyrias.
b. A patient with chronic renal failure was found to had
--- Content provided by FirstRanker.com ---
the following laboratory findings: - serum creatinine 3gm/dL, serum sodium 120 mmol/L, serum potassium 5.8
mmol/L, serum bicarbonate 15 mmol/L.
i. what kind of acid base disturbance is like present in
this case
--- Content provided by FirstRanker.com ---
ii. how does kidney normally regulate extracellular pHV: explain anion gap
V. explain the rationale of investigation to be done in
this patient
a. KFT
--- Content provided by FirstRanker.com ---
b. Explain the biochemical tests that will helpdifferentiating the types of jaundice.
C. Importance and applications of recombinant DNA
technology.
d. Give an account of water distribution and its balance in
--- Content provided by FirstRanker.com ---
the body.e. Explain regulation of genes by repression with
examples.
f. Mutations
Q4. Short Answer Questions
--- Content provided by FirstRanker.com ---
10 x 2 = 20
a. What is the principle of adsorption chromatography
b. Beer and Lambert law
C. Biochemical alterations in protein energy malnutrition
d. Wobble hypothesis
--- Content provided by FirstRanker.com ---
e. Gene therapyf. Molecular basis of thalassemia and cystic fibrosis
g. Functions of nucleotides
h. Tumour markers
i. Name the pre renal conditions that cause increased
--- Content provided by FirstRanker.com ---
blood ureaj. Give two examples of purine analogues used as
anticancer drugs
***