Jabalpur
MBBS First Professional Examination 2018
Summer
Subject- Biochemistry
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Paper-IITime: 3:00 Hours
Maximum Marks :50
a) All questions are compulsory
b) Draw diagrams wherever necessary
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c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question
paper.
d) Do not write anything on the blank portion of
question paper, if written anything such type of act
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will be considered as an attempt to resort to unfairmeans
Q1. Long Answer questions
a. Give a detailed account of transcription process. How
is it regulated? Give the name of inhibiters of
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transcriptionb. Describe the de-novo synthesis of purine nucleotides.
Indicate the clinical uses of inhibitors of purine nucleotide
synthesis
2 x 5 = 10
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Q2. Short Answer Questions
a. Water intoxication
b. Health hazards
c. Renal regulation by acid base balance
d. PCR (Polymerase chain reaction)
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e. Free radicals and anti-oxidantsf. Gout
g. SDA
h. Tumour markers and oncogens
i. Abnormal hemoglobin
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j. Kidney function tests10 x 3 = 30
Q3. Very Short Answer Questions
a. Biologically important nucleotides
b. Role of fiber in the body
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C. Give clinical symptoms of porphyriad. Principles of ELISA
e. Biological carcinogens
f. Cardiac markers
g. Reactive oxygen species (ROS)
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h. Give four characteristics of genetic codei. Significance of quality control in lab
j. Central dogma of molecular biology
10 x 1 = 10
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