Jabalpur
MBBS Second Professional Examination 2022
Subject- Microbiology
Paper- I
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Time: 3:00 HoursMaximum Marks :100
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be
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written strictly according to serial order of questionpaper.
d) Do not write anything on the blank portion of
question paper, if written anything such type of act
will be considered as an attempt to resort to unfair
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meansLong Answer questions
Q1. a. Enumerate different types of nucleic acid
amplification techniques used in diagnostic microbiology.
Discuss principle and applications of PCR.
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b. A 22 years old girl was admitted to hospital withhistory of fever with pattern of step ladder, headache and
abdominal discomfort for last 55 days. On examination,
she was having fever 102?F, tongue was coated and her
pulse rate was 96/mt. she also had mild splenomegaly.
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With this history answer the following questions.1. What is your clinical diagnosis?
II. Which organisms are responsible for this type of
infection?
III. Describe the pathogenesis of this condition.
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IV. Describe sample collection and laboratory diagnosisin detail
2 X 10 = 20
Short Answer Questions
Q2. a. Differences between Gram-positive and Gram-
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negative cell wallb. Type-ll hypersensitivity.
C. MRSA.
d. Pathogenesis of acute rheumatic fever.
e. Laboratory diagnosis of H. pylori infection.
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f. Confidentiality pertaining to patient identity onlaboratory results.
4 X 5= 20
Very Short Answer Questions
Q3. a. Germ tube test
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b. Enumerate hemoparasites.c. Why blood should be withdrawn before administration
of antibiotics for culture?
d. Transformation.
e. Why Gas gangrene is usually associated with cases of
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severe crush injury?
f. Tyndallisation.
g. Complications of Falciparum malaria.
h. Why Biological false positive reaction occurs in VDRL
test?
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i. Enumerate virulence factors of Escherichia coli.j. Draw a well labelled diagram of life cycle of
Entamoeba coli.
1 X 10= 10
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