Jabalpur
MBBS Second Professional Examination Feb-
2023
Subject- Microbiology
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Paper-I (old scheme)Maximum Marks:40
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be
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written strictly according to serial order of questionpaper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1.
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(a) 2. (c)f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
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UFM rules of university.g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 16
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16 x 1/2 = 81) Which Microscope is based on the principle that
differences in the refractive indices of bacterial cells and
the surrounding medium make them clearly visible:
(a) Dark Ground microscope
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(b) Phase contrast microscope(c) Electron microscope
(d) Confocal microscope
2) During which of the following phase bacteria are most
susceptible to antibiotics:
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(a) Lag Phase(b) Log Phase
(c) Stationary Phase
(d) Phase of decline
3) Which of the following statement does not apply to
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ethyl alcohol:(a) it is used mainly as skin antiseptic
(b) it acts by denaturing bacterial proteins
(c) it is used in concentrations of 60-90% in water
(d) it is sporicidal
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4) Acute phase proteins are non specific proteinsproduced during an infection. Which of those mentioned
below is not an acute phase reactants:
(a) CRP
(b) Heat shock protein
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(c) Alpha-1 acid glycoprotein(d) Bence-Jones proteins
5) Which of the following is a pro inflammatory marker:
(a) IL-4
(b) IL-9
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(c) IL-11(d) IL-17
6) Diphtheria toxin has affinity for the following tissue:
(a) Cardiac muscle
(b) Adrenals
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(c) Nerve endings(d) All of the above
7) Which of the following characteristics can differentiate
B. cereus from B. anthracis:
(a) Non-Capsulated
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(b) Motile(c) Non susceptible to gamma phage
(d) All of the above
8) Multidrug resistant tuberculosis (MDR-TB) is due to
M. tuberculosis strain resistant to:
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(a) Rifampicin only(b) Isoniazid and Rifampicin
(c) Isoniazid only
(d) None of the above
9) Anton test is associated with:
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(a) L. monocytogenes(b) Proteus vulgaris
(c) E. cloacae
(d) Hafnia alvei
10) MacConkey's medium with sorbitol instead of lactose
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is used for detection of E. coli strains:
(a) 055
(b) 015
(c) 08
(d) 0157
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11) Which one of the following bacteria is included inHACEK group bacteria:
(a) E. coli
(b) Enterobacter
(c) Eikenella corrodens
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(d) Edwardsiella12) Which of the following bacteria can cause rat bite
fever:
(a) Streptobacillus moniliformis
(b) L. monocytogenes
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(c) Chromobacterium violaceum(d) Flavobacterium meningosepticum
13) Generation time for most of the pathogenic bacteria
is:
(a) 20 sec
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(b) 20 min(c) 20 hours
(d) 20 days
14) Transport medium for Vibrio cholerae is:
(a) Selenite -F
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(b) Amies(c) V-R medium
(d) Stuart's
15) Malta fever is also called as:
(a) Undulating fever
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(b) Relapsing fever(c) Rat bite fever
(d) Cat scratch fever
16) Which of the following is an example of type I
hypersensitivity?
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(a) Lepromin test(b) Casoni test
(c) Tuberculin test
(d) Arthus reaction
Q2. Long Answer Questions
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2 x 5 = 10a. Discuss in details the structure and functions of
bacterial cell wall. Discuss difference in cell wall of gram
positive & gram-negative bacteria.
b. Classify Rickettsia. Write in detail about pathogenesis
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and lab diagnosis of typhus fever.Q3. Brief Answer Questions
4 x 3 = 12
a. Laboratory diagnosis of Gas gangrene.
b. Heterophile agglutination reactions.
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c. Drug resistant tuberculosis.d. Monoclonal antibodies.
Q4. Short Answer Questions
10 x 1 = 10
a. Mention four toxins of Streptococcus pyogenes.
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b. Name four zoonotic diseases caused by bacteria.c. Satellitism.
d. Enumerate the primary mediators of anaphylaxis.
e. Significant bacteriuria.
f. Why Biological false positive reaction occurs in VDRL
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test.g. Which sugar fermentation test is used for
differentiation of Gonococci from Meningococci?
h. Name the most common causative agent of scrofula.
i. Enumerate Sterilization controls used for Autoclave.
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j. What is the working principle of Light microscope?***