Madhya Pradesh Medical Science University,
Jabalpur
MBBS Second Professional Examination
January-2025
Subject- Microbiology
Time: 3 Hours
Maximum Marks :100
a) All questions are compulsory
b) Draw diagrams wherever necessary
written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 10 10 x 1 = 10
for the growth of:
(a) Clostridium tetani (b) Escherichia coli (c)
Pseudomonas (d) None of the above
aeruginosa
Salmonella Typhi in first week of enteric fever is
(a) Blood (b) Faeces (c) Urine (d) Pus
3. Patch test is done for which type of reaction?
(a) Schwartzman reaction (b) Atopy (c) Arthus reaction
4. Which of the following are responsible for hyperacute
rejection?
(a) Preformed antibodies (b) In-situ antibody (c)
Lymphokines (d) All of the these
5. Fasciola hepatica infects
(a) Liver (b) Bile duct (c) Both liver and bile duct (d)
Small intestine
6. Eschar is a pathognomonic feature of -
Spotted fever
7. The route of administration of measles vaccine is
(a) Intramuscular (b) Intradermal (c) subcutaneous (d)
Oral
(a) Present on surface of (b) Transmembrane (c)
Molecules that bind to (d) Nucleotide-binding
phagocytes to bind to receptors present on the surface of
microbes oligomerization domain
receptors to recognize
and dendritic cells intracellular bacterial cell
products
9. Passive immunization of hepatitis B infection is good
(a) Controlling adverse (b) Prevention of carrier (c)
Controlling the spread (d) Prevention of infection
reactions state of disease
10. The following substances can be added to produce an
(a) Glutathione (b) Ascorbic acid (c) Cysteine (d)
Glycerol
Q2. Long Answer Questions 2 x 20 = 40
a. A 6-year-old boy came to the pediatric OPD for school
blood examination revealed microcytic, hypochromic
anaemia. Stool microscopy showed round to oval non-bile-
stained egg with segmented ovum (four blastomeres).
I. Identify the etiological agent responsible for this
II. Enlist the microorganisms causing iron deficiency
anaemia.
III. Describe the life cycle.
IV. Describe the pathogenesis.
clinical condition.
b. A 12 years old male child was admitted in the pediatric
ward with a history of remittent fever which increased
gradually over 10 days. He was admitted with complaints
weakness. On examination he was found to have a
temperature of 102?F with pallor and coated tongue,
relative bradycardia, mild splenomegaly and abdominal
tenderness. His hemogram showed low TLC count,
was positive and non-lactose fermenting colonies were
isolated from MacConkey agar. On further identification,
it was found to be oxidase negative, catalase positive,
negative for indole, citrate and urease and H2S gas was
I. What is your probable diagnosis and etiological agent
responsible for this condition?
II. Describe the pathogenesis.
III. Mention the diagnostic modalities available for this
IV. Add a note on drug resistance for this clinical
condition.
V. Add a note on the treatment and vaccine available
for this clinical condition.
a. Steam sterilization 05
b. What is full disclosure? Mention the exceptional
conditions where full disclosure is not made. 05
c. Classical complement pathway 05
bacterial capsule. 05
e. Describe transferable drug resistance. 05
f. Chikungunya 05
Q4. Short Answer Questions 10 x 2 = 20
b. Draw well labelled diagram of IgA 02
c. Enlist two parasitic causes of splenomegaly and
cholangitis. 02
d. NACO Strategic algorithm Ila and IIb for HIV. 02
f. Enumerate two advantages of live vaccine. 02
g. Mention four differences between MHC class I and
MHC class II. 02
h. Mention four difference between endotoxin and
i. Staging of vaccine vial monitor. 02
j. Name the four rules of autonomy 02
***
Jabalpur
MBBS Second Professional Examination
January-2025
Subject- Microbiology
--- Content provided by FirstRanker.com ---
Paper-I (new scheme)Time: 3 Hours
Maximum Marks :100
a) All questions are compulsory
b) Draw diagrams wherever necessary
--- Content provided by FirstRanker.com ---
c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
--- Content provided by FirstRanker.com ---
(c)f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
--- Content provided by FirstRanker.com ---
UFM rules of university.g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 10 10 x 1 = 10
--- Content provided by FirstRanker.com ---
1. Culture medium with low redox potential is requiredfor the growth of:
(a) Clostridium tetani (b) Escherichia coli (c)
Pseudomonas (d) None of the above
aeruginosa
--- Content provided by FirstRanker.com ---
2. The most important specimen for isolation ofSalmonella Typhi in first week of enteric fever is
(a) Blood (b) Faeces (c) Urine (d) Pus
3. Patch test is done for which type of reaction?
(a) Schwartzman reaction (b) Atopy (c) Arthus reaction
--- Content provided by FirstRanker.com ---
(d) Contact dermatitis4. Which of the following are responsible for hyperacute
rejection?
(a) Preformed antibodies (b) In-situ antibody (c)
Lymphokines (d) All of the these
--- Content provided by FirstRanker.com ---
formation5. Fasciola hepatica infects
(a) Liver (b) Bile duct (c) Both liver and bile duct (d)
Small intestine
6. Eschar is a pathognomonic feature of -
--- Content provided by FirstRanker.com ---
(a) Typhus fever (b) Scrub typhus (c) Q fever (d)Spotted fever
7. The route of administration of measles vaccine is
(a) Intramuscular (b) Intradermal (c) subcutaneous (d)
Oral
--- Content provided by FirstRanker.com ---
8. Toll-like receptors (TLRs) are(a) Present on surface of (b) Transmembrane (c)
Molecules that bind to (d) Nucleotide-binding
phagocytes to bind to receptors present on the surface of
microbes oligomerization domain
--- Content provided by FirstRanker.com ---
mannose rich glycans surface of macrophages likereceptors to recognize
and dendritic cells intracellular bacterial cell
products
9. Passive immunization of hepatitis B infection is good
--- Content provided by FirstRanker.com ---
for -(a) Controlling adverse (b) Prevention of carrier (c)
Controlling the spread (d) Prevention of infection
reactions state of disease
10. The following substances can be added to produce an
--- Content provided by FirstRanker.com ---
anaerobic environment except -(a) Glutathione (b) Ascorbic acid (c) Cysteine (d)
Glycerol
Q2. Long Answer Questions 2 x 20 = 40
a. A 6-year-old boy came to the pediatric OPD for school
--- Content provided by FirstRanker.com ---
health check-up. On examination he had pallor. Peripheralblood examination revealed microcytic, hypochromic
anaemia. Stool microscopy showed round to oval non-bile-
stained egg with segmented ovum (four blastomeres).
I. Identify the etiological agent responsible for this
--- Content provided by FirstRanker.com ---
condition?II. Enlist the microorganisms causing iron deficiency
anaemia.
III. Describe the life cycle.
IV. Describe the pathogenesis.
--- Content provided by FirstRanker.com ---
V. Mention the diagnostic modalities available for thisclinical condition.
b. A 12 years old male child was admitted in the pediatric
ward with a history of remittent fever which increased
gradually over 10 days. He was admitted with complaints
--- Content provided by FirstRanker.com ---
of loss of appetite, pain in abdomen and generalweakness. On examination he was found to have a
temperature of 102?F with pallor and coated tongue,
relative bradycardia, mild splenomegaly and abdominal
tenderness. His hemogram showed low TLC count,
--- Content provided by FirstRanker.com ---
leukopenia with relative lymphocytosis. His blood culturewas positive and non-lactose fermenting colonies were
isolated from MacConkey agar. On further identification,
it was found to be oxidase negative, catalase positive,
negative for indole, citrate and urease and H2S gas was
--- Content provided by FirstRanker.com ---
produced with K/A reaction on TSI agar.I. What is your probable diagnosis and etiological agent
responsible for this condition?
II. Describe the pathogenesis.
III. Mention the diagnostic modalities available for this
--- Content provided by FirstRanker.com ---
condition including the sample collection methods.IV. Add a note on drug resistance for this clinical
condition.
V. Add a note on the treatment and vaccine available
for this clinical condition.
--- Content provided by FirstRanker.com ---
Q3. Brief Answer Questions 6 x 05 = 30a. Steam sterilization 05
b. What is full disclosure? Mention the exceptional
conditions where full disclosure is not made. 05
c. Classical complement pathway 05
--- Content provided by FirstRanker.com ---
d. Mention the methods to demonstrate and functions ofbacterial capsule. 05
e. Describe transferable drug resistance. 05
f. Chikungunya 05
Q4. Short Answer Questions 10 x 2 = 20
--- Content provided by FirstRanker.com ---
a. Enumerate Diarrheagenic E.coli 02b. Draw well labelled diagram of IgA 02
c. Enlist two parasitic causes of splenomegaly and
cholangitis. 02
d. NACO Strategic algorithm Ila and IIb for HIV. 02
--- Content provided by FirstRanker.com ---
e. Laboratory diagnosis of fungal infections. 02f. Enumerate two advantages of live vaccine. 02
g. Mention four differences between MHC class I and
MHC class II. 02
h. Mention four difference between endotoxin and
--- Content provided by FirstRanker.com ---
exotoxin. 02i. Staging of vaccine vial monitor. 02
j. Name the four rules of autonomy 02
***