Jabalpur
MBBS Second Professional Examination April-
2024
Subject- Pathology
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Paper-I (new scheme)Time: 3:00 Hours
Maximum Marks :100
a) All questions are compulsory
b) Draw diagrams wherever necessary
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c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question
paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
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with black or blue pen in brackets; for example: - 1.(a) 2. (c)
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
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counted in marks and action will be taken according toUFM rules of university.
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
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Q1. Total MCQs: 101. Caseation necrosis occurs in 10 x 1 = 10
(a) Infective hepatitis
(b) Tuberculosis
(c) Amoebiasis
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(d) Glomerulonephritis2. Eosinophilia occurs in
(a) Viral infections
(b) Fungal infections
(c) Acute pyogenic
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infections(d) Parasitic infections
3. Healing by first intention requires
(a) Clean wounds
(b) Minimal loss of tissue
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(c) No foreign bodies(d) All of the above
4. All of the following are mediators of inflammation
except-
(a) Tumor necrosis factor- (b) Interleukin-1
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alpha(c) Myeloperoxidase
(d) Prostaglandin
5. Vasoactive amine involved in inflammation is -
(a) Histamine
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(b) Rennin(c) Angiotensin
(d) Endothelin
6. Zeihl Neelsen stain detects-
(a) Gram negative bacilli
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(b) Gram positive bacilli(c) Acid fast bacilli
(d) Gram positive cocci
7. Factor VIII deficiency causes-
(a) Hemophilia A
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(b) Hemophilia B(c) Hemophilia c
(d) Hemophilia D
8. Iron absorption is increased by -
(a) Phytates
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(b) Tannates(c) Plant food
(d) Ascorbic acid
9. True about apoptosis are all except-
(a) Inflammation is present (b) Chromosomal
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breakage(c) Clumping of chromatin
(d) Cell shrinkage
10. Morphologic changes in necrosis include
(a) Damage of cell
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membrane(b) Pyknosis
(c) Karyorrhexis
(d) All of the above
Q2. Long Answer Questions
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a. A 20-year-old girl complains of weakness, easy
fatigability and breathlessness of 6 months duration. She
also complains of heavy menstrual bleeding every month.
On examination, she is pale and has spoon shaped brittle
nails and cheilosis. 2 x 20 = 40
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1. What is provisional diagnosis?II. Discuss its etiopathogenesis.
III. Describe the peripheral and bone marrow findings.
IV. Describe laboratory investigation.
b. A 55year old male patient presents with progressive
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fatigue, weight loss and edema in legs. Laboratory testsreveal elevated levels of protein in urine, Congo red was
used to diagnose it in abdominal fat aspirates. Deposits in
spleen show sago spleen and lardaceous spleen. On
physical examination, he has hepatomegaly and
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macroglossia.1. Identify the clinical condition
II. What are its types and classification?
III. What is its pathogenesis
IV. Systemic features on different organs
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Q3. Brief Answer Questionsa. Define inflammation. Describe the vascular changes in
acute inflammation. 6 x 05 = 30
b. Define necrosis. Describe its types with suitable
examples
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C. Define and describe the pathogenesis of AIDS.e. Define hypersensitivity reaction and its different types,
with 1 example each
d. Difference between metastatic and dystrophic
calcification
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f. Define shock with pathogenesis of septic shock.Q4. Short Answer Questions
a. Virchow's triad 10 x 2 = 20
b. Paraneoplastic syndrome
C. Embolism
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d. Pancytopeniae. Enumerate giant cell
f. Difference between intravascular and extravascular
hemolysis
g. Enumerate factors that influences tissue repair
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h. Enumerate 4 microscopic findings of granulomai. Write differences between myeloblasts and
lymphoblasts
j. Causes of chronic granulomatous inflammation
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