Jabalpur
MBBS Second Professional Examination
January-2025
Subject- Pathology
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Paper- II (new scheme)Time: 3:00 Hours
Maximum Marks :100
a) All questions are compulsory
b) Draw diagrams wherever necessary
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c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
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(c)f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
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UFM rules of university.g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Total MCQs: 10
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Q1. 10 x 1 = 101. Which virus is not transmitted parenterally?
(a) Hepatitis B
(b) Hepatitis C
(c) Hepatitis G
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(d) Hepatitis E2. In which condition are Aschoff bodies seen?
(a) Rheumatoid arthritis
(b) Tuberculosis
(c) Rheumatic heart disease
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(d) Sarcoidosis3. The most common primary site for the origin of Paget's
disease is:
(a) Nipple
(b) Anal canal
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(c) Liver(d) Penis
4. Which of the following is the most common cause of
myocardial infarction?
(a) Hypertension
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(b) Coronary artery thrombosis(c) Aortic stenosis
(d) Pulmonary embolism
5. In which of the following conditions are Reed-
Sternberg cells seen?
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(a) Non-Hodgkin lymphoma(b) Hodgkin lymphoma
(c) Chronic lymphocytic leukemia
(d) Multiple myeloma
6. Hypothyroidism is associated with all of the following
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except:(a) Cretinism
(b) Autism
(c) Cold intolerance
(d) Weight gain
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7. Not a germ cell tumor:(a) Seminoma
(b) Yolk sac tumor
(c) PNET
(d) Dysgerminoma
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8. Tamm-Horsfall protein is produced by:(a) Distal tubules
(b) Ureter
(c) Loop of Henle
(d) Collecting duct
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9. Multiple sclerosis is an autoimmune disease thataffects the:
(a) Brain
(b) Spinal cord
(c) Peripheral nerves
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(d) Muscles10. Most common cause of Nephrotic syndrome in
children is:
(a) RPGN
(b) PSGN
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(c) Minimal change disease
(d) Focal GN
Long Answer Questions
Q2. 2 x 20 = 40
1. A 52-year-old woman presents with a palpable lump in
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her right breast. On examination, the lump is hard,irregular, and fixed to the underlying tissue. There are
palpable axillary lymph nodes. A mammogram shows a
mass with micro calcifications. A biopsy is performed.
Based on the clinical presentation and imaging
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findings, what is the most likely histological diagnosis?(05 Mark)
II. What are the key prognostic factors for breast
carcinoma? (05 Mark)
III. Describe the significance of immune histochemical
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staining in the diagnosis and prognosis of breastcarcinoma. (05 Mark)
IV. What are the histological features of Paget's disease
of the breast? (05 Mark)
a.
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b. A middle-aged known smoker presented withpersistent cough with expectoration and evening raise in
temperature in the past two weeks. Chest x ray identified
consolidation in the lower portion of the upper lobe of
right lung. Hilar lymphadenopathy was noted. Sputum
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examination detected acid fast bacilli.1. What is the most probable diagnosis? (5marks)
II. Discuss the pathogenesis. (5marks)
III. Describe the gross and microscopic findings
(5 marks)
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IV. Mention two complications (5marks)Brief Answer Questions
Q3. 6 x 05 = 30
a. What are the common causes of anemia, and how are
they classified based on their morphology and etiology?
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b. Discuss the diagnostic pathologic criteria of rheumaticheart disease
C. Enumerate the CSF findings in tuberculous meningitis
d. Describe in detail about melanoma?
e. How does hypertension lead to left ventricular
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hypertrophy?f. Enlist the Classification of ovarian tumors
Short Answer Questions
Q4. 10 x 2 = 20
a. Describe various types of giant cells?
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b. Paraneoplastic SyndromeC. Enlist histopathological features of Papillary of
Carcinoma thyroid
d. Explain the characteristic renal histopathological
finding in diabetic nephropathy and its clinical
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significance.
e. Mention four causes of Congenital Hyperbilirubinemia
f. Write the gene involved in retinoblastoma?
g. Enumerate HPV associated malignancies
h. Write all the parameters of complete blood count
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report (CBC)?i. Write the battery of test for viral hepatitis?
j. Wilms Tumor
***
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