Download ABVMU MBBS 2nd Year 2024 December Pathology Paper I MCQs Question Paper

MBBS DEGREE - IInd PROFESSIONAL - REGULAR
PATHOLOGY - PAPER - I
SECTION A - Multiple Choice Questions (MCQs)
PAPER CODE : 2411130004 SET : D
Note: Choose one correct answer in the OMR sheet provided. No overwriting should be

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done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Microangiopathic hemolytic anemia is associated with which of the following conditions:
a) Thalassemia
b) Disseminated intravascular coagulation

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c) Sickle cell anemia
d) Pernicious anemia
2. The mediator primarily responsible for pain during inflammation is:
a) Bradykinin
b) Leukotriene B4

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c) Histamine
d) Tumor necrosis factor-alpha
3. Chronic lymphocytic leukemia (CLL) is most commonly diagnosed in which age group?
a) Adolescents
b) Young adults

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c) Children
d) Older adults
4. Which type of white blood cell is most likely to be elevated during an allergic reaction?
a) Neutrophils
b) Eosinophils

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c) Lymphocytes
d) Basophils
5. A 25-year-old male presents with tall stature, gynecomastia, and small testes.
Chromosomal analysis reveals 47, XXY. Which of the following features is most
characteristic of his condition?

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a) Male infertility
b) Cardiomegaly
c) Intellectual disability
d) Microcephaly
6. Which of the following is an example of an autoimmune disease?

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a) Tuberculosis
b) Rheumatoid arthritis
c) HIV/AIDS
d) Malaria

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7. Which of the following is NOT a cardinal sign of acute inflammation?

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a) Swelling
b) Fever
c) Redness
d) Pain
8. Type II hypersensitivity reactions involve:

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a) Immune complex deposition
b) T-cell mediated cytotoxicity
c) Antibody-mediated cell destruction
d) Delayed-type hypersensitivity
9. A 40-year-old woman presents with memory impairment, irritability, and abdominal pain.

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She lives in an old house with peeling paint. Blood tests reveal microcytic anemia. What is
the most likely diagnosis?
a) Thalassemia
b) Lead poisoning
c) Hemochromatosis

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d) Mercury poisoning
10. The key enzymes involved in the execution phase of apoptosis are:
a) Cyclins
b) Kinases
c) Caspases

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d) Ligases
11. HIV primarily targets which cells of the immune system?
a) B lymphocytes
b) Neutrophils
c) T lymphocytes

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d) Macrophages
12. Pancytopenia with hypercellular marrow is characteristic of:
a) Aplastic anemia
b) Paroxysmal nocturnal hemoglobinuria
c) Myelofibrosis

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d) Myelodysplastic syndrome
13. Autophagy is a cellular process involved in:
a) Cell cycle progression
b) Cellular degradation
c) DNA replication

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d) Protein synthesis
14. Cystic fibrosis is caused by:
a) A chromosomal abnormality
b) Environmental factors
c) A single gene mutation

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d) Unknown factors

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15. Howell-Jolly bodies are seen in:
a) Asplenia
b) Hemolytic anemia
c) Iron deficiency anemia

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d) Megaloblastic anemia
16. The following is a hallmark of reversible cell injury:
a) Mitochondrial swelling
b) Pyknosis
c) Karyorrhexis

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d) Cytoplasmic eosinophilia
17. Telomere shortening is associated with:
a) Cellular immortality
b) Cellular senescence
c) Increased cellular replication

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d) Enhanced DNA repair
18. Which of the following is a reversible cell injury?
a) Apoptosis
b) Cellular swelling
c) Necrosis

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d) Liquefactive necrosis
19. How is Fresh Frozen Plasma stored?
a) Refrigerated at 2?8?C
b) Frozen at -18?C or colder
c) At room temperature

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d) Lyophilized
20. Sirtuins are a family of proteins involved in:
a) Cellular senescence
b) Metabolic regulation
c) DNA repair

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d) Oxidative stress

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