MBBS DEGREE - IInd PROFESSIONAL - SUPPLEMENTARY EXAMINATION - JUNE 2024
PHARMACOLOGY - PAPER - I
SECTION A - Multiple Choice Questions (MCQs)
PAPER CODE : 2421130005
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SET : CNote: Choose one correct answer in the OMR sheet provided. No overwriting should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Which one of the following compounds is a microsomal enzyme inhibitor?
a) Phenobarbitone
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b) Rifampicinc) Erythromycin
d) Glucocorticoids
2. Which of the following is used as dissociative anesthesia?
a) Morphine
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b) Fentanylc) Ether
d) Ketamine
3. Which of the following is used as a tocolytic agent?
a) Phenylephrine
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b) Isoxsuprinec) Amphetamine
d) Ephedrine
4. Category of drugs used for rare diseases are called:
a) Orphan drugs
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b) Non-essential drugsc) Not approved drugs
d) Costly drugs
5. Adrenaline injected with a local anesthetic:
a) Reduces systemic toxicity
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b) Reduces local toxicityc) Makes injection less painful
d) Shortens duration of anesthesia
6. Adverse effect of 2 agonists:
a) Hypomagnesemia
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b) Hypoglycemiac) Hypokalemia
d) Hypophosphatemia
7. Apparent Vd exceeds body fluid volume if drug is:
a) Slowly eliminated
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b) Sequestered in tissuesc) Highly bound to plasma proteins
d) Poorly soluble in plasma
8. Eutectic lignocaine-prilocaine unique property:
a) Anesthetises unbroken skin
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b) Causes motor blockade onlyc) Strong vasoconstrictor action
d) Not absorbed after application
9. Uricosuric agent used in chronic gout:
a) Probenecid
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b) Colchicinec) Febuxostat
d) Allopurinol
10. Most rapid acting route:
a) Sublingual
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b) Oralc) Intravenous
d) Intramuscular
11. True statement about first order kinetics:
a) Constant amount eliminated
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b) Alcohol elimination is first orderc) Half-life depends on concentration
d) Constant fraction eliminated
12. A partial agonist antagonises a full agonist because it has:
a) Low affinity, high intrinsic activity
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b) High affinity, low intrinsic activityc) High affinity, no intrinsic activity
d) No affinity, low intrinsic activity
13. Enhancer of levodopa bioavailability in Parkinson's:
a) Ropinirole
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b) Amantadinec) Selegiline
d) Entacapone
14. Drug not inducing mydriasis:
a) Ephedrine
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b) Phentolaminec) Cocaine
d) Phenylephrine
15. H1 antihistaminic not preferred for fine tasks:
a) Azelastine
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b) Fexofenadinec) Promethazine
d) Ebastine
16. Drug causing haemolysis in G6PD deficiency:
a) Paracetamol
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b) Ampicillinc) Primaquine
d) Dopamine
17. Antiepileptic used in migraine prophylaxis:
a) Sumatriptan
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b) Propranololc) Flunarizine
d) Topiramate
18. Atropine is contraindicated in:
a) Myasthenia gravis
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b) Early mushroom poisoningc) Glaucoma
d) Organophosphate poisoning
19. Which of the following is a prodrug?
a) Captopril
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b) Ampicillinc) Phenytoin
d) Levodopa
20. Microsomal enzyme induction can cause:
a) Physical dependence
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b) Tolerancec) Idiosyncrasy
d) Psychological dependence
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