Download ABVMU MBBS 2nd Year 2024 March Pathology Paper I MCQs Question Paper

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH-2024
PATHOLOGY - PAPER - I
SECTION A - Multiple Choice Questions (MCQs)
PAPER CODE : 2411130004

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SET : C
Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Smith antigen (Sm) is associated with:
a) Systemic sclerosis

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b) Systemic lupus erythematosus
c) Sjogren syndrome
d) Rheumatoid arthritis
2. The major fibril protein associated with hemodialysis associated amyloidosis is:
a) A2m

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b) ATTR
c) AA
d) AL
3. Mutation in globin gene is seen in:
a) Sickle cell anemia

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b) Hereditary spherocytosis
c) Thalassemia
d) Polycythemia
4. In Marfan syndrome the defect is in:
a) Collagen type II

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b) Collagen type III
c) Fibrillin I
d) Fibrillin II
5. White infarcts occur in:
a) Small intestine

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b) Oesophagus
c) Lung
d) Kidney

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6. Touton giant cells are seen in:
a) Leprosy

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b) Syphilis
c) Sarcoidosis
d) Xanthogranuloma
7. All of the following are tumor suppressor genes except:
a) pRB

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b) BCL2
c) p53
d) BRCA1
8. HIV replication results in:
a) Decreased count of CD8+ T cells

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b) Increased count of CD8+ T cells
c) Decreased count of CD4+ T cells
d) Increased count of CD4+ T cells
9. A tumour is called clonal, when the incurred genetic damage is in:
a) Stem cells

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b) Heterogenous cells
c) Single precursor cell
d) Multiple precursor cell
10. Which of these diseases listed is an X-linked disorder:
a) Haemophilia A

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b) Polycystic kidney disease
c) Neurofibromatosis
d) Cystic fibrosis
11. Tay-Sach's disease caused by inability to metabolise:
a) Sphingolipids

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b) Lipoproteins
c) Glycolipids
d) Gangliosides
12. Hyperacute graft rejection is an example of this type of hypersensitivity reaction:
a) Type III

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b) Type IV
c) Type I
d) Type II

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13. Effector white blood cells of the innate immune system are:
a) Lymphocytes

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b) NK cells
c) Dendritic cells
d) Neutrophils
14. Red cell distribution width (RDW) is used for estimation of:
a) Chromasia

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b) Hemolysis
c) Poikilocytosis
d) Anisocytosis
15. Sickle cell trait protects against:
a) Trypanosomiasis

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b) Leishmaniasis
c) Filariasis
d) Malaria
16. Trisomy 13 is defined as:
a) Cri du chat syndrome

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b) Patau syndrome
c) Edward syndrome
d) Klinefelter syndrome
17. Which variant of Hodgkin's lymphoma has best prognosis:
a) Mixed cellularity

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b) Nodular sclerosis
c) Lymphocyte predominant
d) Lymphocyte depleted
18. EBV is associated with:
a) Hepatocellular carcinoma

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b) Carcinoma colon
c) Nasopharyngeal carcinoma
d) Esophageal carcinoma
19. The combination of HLA allele in each individual is called:
a) Diplotype

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b) Tetratype
c) Prototype
d) Haplotype

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20. Chronic granulomatous inflammation is seen in:
a) Sarcoidosis

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b) Pneumonia
c) Diphtheria
d) Typhoid
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