MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH-2024
PHARMACOLOGY - PAPER - I
SECTION A - Multiple Choice Questions (MCQs)
PAPER CODE : 2411130005
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SET : BNote: Choose one correct answer in the OMR sheet provided. No overwriting should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Atropine does not antagonise the following feature of anticholinesterase
poisoning:
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a) Central excitationb) Muscle paralysis
c) Hypotension
d) Bronchoconstriction
2. Which of the following compounds acts as a benzodiazepine antagonist?
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a) Naloxoneb) Flurazolidone
c) Flumazenil
d) Naltrexone
3. Bromocriptine acts as:
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a) Peripheral carboxylase inhibitorb) COMT inhibitor
c) Dopamine agonist
d) MAO inhibitor
4. Which drug does not act by cAMP pathway?
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a) Somatostatinb) Glucagon
c) Estrogen
d) ACTH
5. Succinylcholine is the preferred muscle relaxant for tracheal intubation because:
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a) It does not alter heart rate or blood pressureb) It does not cause histamine release
c) It produces rapid & complete paralysis of respiratory muscles with quick
recovery
d) It does not produce postoperative muscle soreness
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6. Drug of choice for alcohol withdrawal is:
a) Naltrexone
b) Diazepam
c) Disulfiram
d) Chlordiazepoxide
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7. Derivative of morphine used for diarrhea is:a) Diphenoxylate
b) Pethidine
c) Oxymorphine
d) Codeine
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8. The most vulnerable period of pregnancy for the causation of foetalmalformations due to drugs is:
a) 56?84 days of gestation
b) Second trimester
c) 18?55 days of gestation
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d) 36 weeks onwards9. The neuromuscular blocker that does not need reversal of action by neostigmine
at the end of the operation is:
a) Doxacurium
b) Pancuronium
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c) d-Tubocurarined) Mivacurium
10. When the same dose of a drug is repeated at half-life intervals, the steady-state
(plateau) plasma drug concentration is reached after:
a) 4?5 half lives
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b) 6?7 half livesc) 2?3 half lives
d) 8?10 half lives
11. An immunologically mediated reaction to drug producing stereotyped symptoms
unrelated to its pharmacodynamic actions is:
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a) Supersensitivityb) Intolerance
c) Hypersensitivity
d) Idiosyncrasy
12. Bimatoprost is used as:
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a) Systemically to maintain patency of ductus arteriosusb) Cervical gel for ripening of cervix
c) Topical eye drops in open angle glaucoma
d) Orally for gastric ulcer
13. Which statements about anti-epileptics is false?
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a) Carbamazepine can be used in trigeminal neuralgiab) Diazepam is an anticonvulsant drug
c) Phenytoin and carbamazepine act by prolonging the inactivated state of Na+
channels
d) Lamotrigine mainly acts by causing GABA mediated Cl- channel opening
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14. If the total amount of a drug present in the body at a given moment is 2.0 g andits plasma concentration is 25 ?g/ml, its volume of distribution is:
a) 80 L
b) 60 L
c) 100 L
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d) 50 L15. Drug which is used as a short-term inotropic in severe congestive heart failure
& has selective adrenergic 1 agonistic activity but no dopaminergic agonistic
activity:
a) Dobutamine
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b) Amrinonec) Dopamine
d) Milrinone
16. Which drug is used for differentiating myasthenia gravis from cholinergic crisis?
a) Neostigmine
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b) Atropinec) Edrophonium
d) Acetylcholine
17. In which phase of clinical trials, post-marketing surveillance of a drug is carried
out:
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a) Phase IIb) Phase III
c) Phase I
d) Phase IV
18. The bladder trigone and prostatic muscles are relaxed by:
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a) Adrenergic 1 antagonistsb) Adrenergic 2 agonists
c) Adrenergic 1 agonists
d) Adrenergic 2 antagonists
19. Drugs used for cessation of smoking are all except:
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a) Bupropionb) Varenicline
c) Buspirone
d) Nicotine
20. Agonistic action on which of the following adrenergic receptors located on ciliary
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epithelial cells reduces aqueous secretion:a) 2 receptor
b) 1 receptor
c) 1 receptor
d) 2 receptor
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