Download ABVMU MBBS 2nd Year 2024 March Pharmacology Paper II MCQS Question Paper

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH 2024
PHARMACOLOGY - PAPER - II
SECTION A - Multiple Choice Questions (MCQs)
PAPER CODE : 2412130005

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SET : B
Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.
Time: 20 Minutes (20 x 1 = 20 MARKS)
1. Find the drug which has been associated with aplastic anaemia as a deadly
adverse effect:

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a) Ampicillin
b) Tetracycline
c) Chloramphenicol
d) Chloroquine
2. Which of the following drug is used mainly to lower postprandial blood glucose

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levels?
a) Acarbose
b) Sitagliptin
c) Sulfonylurea
d) Repaglinide

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3. All of the following drugs act on nucleic acids except:
a) Linezolid
b) Fluoroquinolones
c) Nalidixic acid
d) Rifampicin

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4. Which is an oral factor Xa inhibitor?
a) Dabigatran
b) Rivaroxaban
c) Fondaparinux
d) Argatroban

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5. Which one of the following compounds kills bacteria by damaging the cell wall of
bacteria?
a) Rifampicin
b) Cefixime
c) Gentamicin

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d) Chloramphenicol

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6. Which anti-tubercular drug can result in peripheral neuropathy due to deficiency
of pyridoxine?
a) Rifampicin
b) Isoniazid

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c) Pyrazinamide
d) Ethambutol
7. Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher
concentrations?
a) Tetracycline

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b) Erythromycin
c) Ampicillin
d) Chloramphenicol
8. Drug of choice for precocious puberty in girls is:
a) Danazol

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b) GnRH analogue
c) Medroxyprogesterone acetate
d) Cyproterone acetate
9. Which of the following hypolipidemic drugs is most effective in raising
HDL-cholesterol level and lowers serum triglycerides:

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a) Fenofibrate
b) Nicotinic acid
c) Pravastatin
d) Cholestyramine
10. Which one of the following anticancer drugs belongs to the alkylating agents

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subdivision of chemotherapeutic agents?
a) Vincristine
b) Paclitaxel
c) Mercaptopurine
d) Procarbazine

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11. Substitution of which amino acid in place of alanine would increase the
absorbance of proteins at 280 nm?
a) Arginine
b) Phenylalanine
c) Tryptophan

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d) Leucine

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12. A professional body builder on high protein diet went for routine health
check-up. Which of these parameters is expected to be high in blood sample in this
case?
a) Serum uric acid

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b) Serum bilirubin
c) Serum urea
d) Serum creatinine
13. An infant came to OPD with complaints of dark urine stained diaper which on
exposure becomes darker. Probable diagnosis:

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a) Phenylalanine hydroxylase deficiency
b) Hepatic transaminase deficiency
c) Fumaryl acetoacetate hydrolase deficiency
d) Homogentisate oxidase deficiency
14. What is the mechanism of allopurinol in lowering serum uric acid levels?

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a) Non-competitive inhibition
b) Feedback inhibition
c) Allosteric inhibition
d) Suicidal inhibition
15. A 6-year-old presented to eye OPD with complaint of diminished vision in both

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eyes. Physical examination showed arachnodactyly, dislocation of lens and
hyperextension of joints. Identify the disease and defective protein associated:
a) Marfan's syndrome ? Fibrillin I protein
b) Menke's syndrome ? Lysyl oxidase
c) Osteogenesis imperfecta ? Collagen type I

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d) Ehler?Danlos syndrome ? Lysyl oxidase
16. Red man syndrome is caused by which drug?
a) Clindamycin
b) Linezolid
c) Teicoplanin

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d) Vancomycin
17. Hypothyroidism is a possible consequence of prolonged therapy with:
a) Mexiletine
b) Amiodarone
c) Procainamide

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d) Sotalol

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18. The following quinolone antimicrobial agent is not useful in systemic infections:
a) Ofloxacin
b) Lomefloxacin
c) Pefloxacin

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d) Nalidixic acid
19. Which of the following drugs is NOT a GpIIb/IIIa antagonist:
a) Abciximab
b) Tirofiban
c) Prasugrel

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d) Eptifibatide
20. Which of the following drug has dual action on HIV and hepatitis B virus?
a) Emtricitabine
b) Enfuvirtide
c) Acyclovir

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d) Abacavir
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