NOTE:
Attempt all questions.
This question paper consists of two sections: Section A- Multiple Choice Questions and Section B- Theory Questions.
Both the sections have different paper code. Write correct paper code on respective sheet
Write correct MCQ paper set on OMR sheet
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Answer MCQs on the provided OMR sheet and theory questions on the provided answer booklet.
SECTION B - THEORY QUESTIONS
PAPER CODE: 2411230005
Q.1 Long Answer Question 15 MARKS
- i) Describe antidepressant drugs. 9 marks
- ii) Elaborate the mechanism of action, and potential side effects of selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression and anxiety disorders. 6 marks
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Q.2 Clinical Case Scenario based Structured Question 15 MARKS
A 60-year-old man has occasional episodes of gout that are painful and debilitating. He requires drugs to treat the symptoms of acute gout attacks and to prevent recurrent attacks.
- i) What causes this patient's painful episodes of gout? 3 marks
- ii) What is the therapeutic rationale for the drugs used to treat gout in 4 marks this patient?
- iii) This patient is prescribed colchicine. What is the mechanism of action of this drug? 4 marks
- iv) How does probenecid increase the excretion of uric acid? 4 marks
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Q.3 Short Note Question (Within 500 Words) 5 x 6 = 30 MARKS
- i) Factors affecting absorption of a drug
- ii) Lithium
- iii) Selective COX-2 inhibitors
- iv) Management of status epilepticus
- v) Informed Consent Process in clinical practice
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Q.4 Short Answer Questions (Within 100 Words) 5 x 4 = 20 MARKS
- i) Why long-acting beta-agonists (LABAs) are commonly used in combination with inhaled corticosteroids for the management of asthma?
- ii) Compare and contrast dopamine and dobutamine.
- iii) What is enterohepatic circulation and how it affects the elimination half-life of drugs?
- iv) Pharmacotherapy of organophosphorus poisoning
- v) Leukotriene Receptor Antagonists
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