Download MPMSU MBBS Final Year May 2022 Subject General Medicine Paper II Question Paper

Time: 3 Hours Maximum Marks : 60

Instructions:

1. All questions are compulsory.
2. Draw diagrams wherever necessary.
3. Answers of Questions and Sub-questions must be written strictly according to the serial order of question paper.

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4. MCQs have to be answered in theory answer book.
5. Please write MCQ answers neatly in serial order with brackets, e.g. 1.(a) 2.(b).
6. MCQs answered only once; cutting, erasing or whitener is malpractice.

Q.1 Total MCQs : 20 20 × ½ = 10

1. RIFLE criteria is used for diagnosis of:
   1. Acute Myocardial infarction

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   2. Stroke
   3. Liver injury
   4. Acute kidney injury
2. Earliest clinical feature of diabetic nephropathy is:
   1. Increase serum creatinine

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   2. Hyperkalemia
   3. Microalbuminuria
   4. Hematuria
3. SIADH is not associated with:
   1. Hyponatremia

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   2. Hypouricemia
   3. Decrease plasma osmolality
   4. High urine sodium
4. Which of the following are characteristics of DM:
   1. Encephalopathy

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   2. Myelopathy
   3. Neuropathy
   4. Convulsions
5. HbA1C level indicates:
   1. Long-term sugar control

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   2. Chronic pancreatitis
   3. Chronic liver disease
   4. Hepatorenal syndrome
6. Which is 1st indicator of response to therapy in hypothyroidism:
   1. Weight loss

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   2. Restoration of ankle reflex
   3. Skin and hair changes
   4. GI symptoms
7. Investigation of choice for dysphagia for solids:
   1. Barium swallow

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   2. Endoscopy
   3. X-ray chest
   4. CT scan
8. Which is not a feature of pheochromocytoma:
   1. Headache

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   2. Sweating attacks
   3. Weight gain
   4. Palpitation
9. Which of following is not a feature of tumour lysis syndrome:
   1. Hyperuricemia

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   2. Hyperkalemia
   3. Hypokalemia
   4. Hypocalcemia
10. Most common cause of Primary hyperparathyroidism:
    1. Iatrogenic

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    2. Medullary carcinoma of thyroid
    3. Parathyroid adenoma
    4. Parathyroid hyperplasia
11. Which of the following is not a drug for leprosy:
    1. Rifampin

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    2. Isoniazid
    3. Ofloxacin
    4. Moxifloxacin
12. Which insulin is given in DKA:
    1. Actrapid

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    2. Mixtard
    3. Degludec
    4. Glargine
13. Which drug is useful in heart failure:
    1. Dapagliflozin

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    2. Teneligliptin
    3. Vildagliptin
    4. Empagliflozin
14. Which is not a feature of hypercalcemia:
    1. Laryngospasm

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    2. Paresthesia
    3. Carpopedal spasm
    4. Myocardial infarction
15. Which is causative agent of Lyme disease?
    1. Borrelia burgdorferi

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    2. Francisella tularensis
    3. Yersinia pestis
    4. Rickettsia rickettsii
16. Chvostek's sign is commonly associated with:
    1. Hypokalemia

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    2. Hypocalcemia
    3. Hypercalcemia
    4. Hyperkalemia
17. Characteristic respiratory pattern of metabolic acidosis is known as:
    1. Kussmaul respiration

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    2. Cheyne-Stokes respiration
    3. Biot's respiration
    4. None of the above
18. Target hemoglobin in CKD on hemodialysis is:
    1. 8-9 gm%

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    2. 9-10 gm%
    3. 10-11 gm%
    4. 11-12 gm%
19. Most common lesion in HIV-associated nephropathy:
    1. Diffuse Proliferative GN

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    2. IgA nephropathy
    3. Membrano-proliferative GN
    4. Focal Segmental Glomerulosclerosis
20. Most common mitochondrial inheritance disease:
    1. MELAS

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    2. CPEO
    3. Leber's hereditary optic neuropathy
    4. Myoclonic epilepsy & ragged red fibers

Q.2 Long Answer Questions 4 × 5 = 20

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1. Write in brief causes of nephrotic syndrome and treatment of nephrotic syndrome.
2. Describe aetiology, clinical features, investigations & management of hyperthyroidism.
3. Discuss aetiopathogenesis, clinical features, investigations & management of enteric (typhoid) fever.
4. Describe clinical features and complications of COVID-19 disease.

Q.3 Short Answer Questions 4 × 3 = 12

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1. What are complications of long standing diabetes?
2. Clinical features and management of scabies.
3. Clinical characteristics of Turner's Syndrome.
4. Dapagliflozin.

Q.4 Very Short Answer Questions 9 × 2 = 18

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1. Features of Cyanocobalamin deficiency.
2. Treatment of malaria.
3. Four features of obsessive compulsive disorder.
4. Recent definition of Fever of Unknown Origin (FUO).
5. Definition criteria for Metabolic Syndrome.

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6. Enumerate four causes of Normal Anion Gap Metabolic Acidosis.
7. Four second-line drugs for treatment of tuberculosis.
8. Four drugs for treatment of leprosy.
9. Four causes of superior vena cava syndrome.

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