Download VNSGU (Veer Narmad South Gujarat University or South Gujarat University) MBBS 2nd Year (Second Year) 2024 February-March 2106000102030101 Microbiology Paper I Previous Question Paper
2106000102030101
Examination February ? March 2024
SECOND MBBS
MICROBIOLOGY ( PAPER - I ) - LEVEL 3
[Time: Three Hours]
[Max. Marks: 100]
Instructions:
Seat No:
1. Fill up strictly the following details on your answer book
a. Name of the Examination : SECOND MBBS
b. Name of the Subject : MICROBIOLOGY ( PAPER - I ) -
LEVEL 3
c. Subject Code No : 2106000102030101
2. Sketch neat and labelled diagram wherever necessary with blue
pen/pencil only.
3. Figures to the right indicate full marks of the question.
4. All questions are compulsory.
Student's Signature
5. Write heading of each question properly.
6. Write legibly.
SECTION 01
(General Microbiology, Immunology, Infections of Blood stream &
cardiovascular system, Gastro intestinal react & Hepatobilliary
system)
Q.1 MCQs
(1x20= 20)
1. Most common protozoan parasite responsible for Steatorrhea is:
A. Giardia lamblia
B. Entamoeba histolytica
C. Entamoeba coli
D. Enteromonas hominis
2. Test done to differentiate between Pathogenic and nonpathogenic
strains of Staphylococcus aureus is
A. Oxidase test
B. Catalase test
C. Coagulase test
D. Glucose fermentation test
3. Dengue virus infection is transmitted by
A. Culex mosquito
B. Anopheles mosquito
C. Ades aegypti
D. Tick
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4. Infection with Plasmodium falciparum is suspected if the infected
RBC is
A. Normal in size
B. showing multiple infections
C. Both (A) and (B)
D. shows motile form inside the RBCs
5. Which of these techniques is not used for cultivation of viruses
A. Inanimate culture media
B. Tissue culture
C. Animal inoculation
D. Embryonated egg
6. Rocky mountain spotted fever is due to
A. R. rickettsii
B. R. typhi
C. R. prowazekii
D. R. conorii
7. IgE
A. Protects body fluids
B. Protects body surfaces
C. Protects blood stream
D. Mediates reaginic hypersensitivity
8. Negri bodies of Rabies are
A. Intracytoplasmic eosinophilic inclusions with basophilic
inner granules
B. Intracytoplasmic basophilic inclusions with basophilic inner
granules
C. Intracytoplasmic acidophilic inclusions with basophilic inner
granules
D. None of the above
9. Transduction is a method of gene transfer from one bacteria to
another by
A. Passage of genetic material through sex pilli
B. Direct cell to cell contact and protoplasmic fusion
C. Plasmids transfer
D. Cross infecting Bacteriophages
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10. In Gram's staining " Gull wing" shape is seen in
A. Yersinia pestis
B. Vibrio cholerae
C. Acinetobacter
D. Campylobacter
11. CBNAAT is
A. Chip based nucleic acid amplification test
B. Cartridge based nucleic acid amplification test
C. Both (a) and (b)
D. None of the above
12. Production of germ tube within 2 hours serves as identification
character for
A. Ray fungus
B. Cryptococcus neoformans
C. Rhizopus
D. Candida albicans
13. Which of the following parasites cause megaloblastic anemia
A. Diphyllobothrium latum
B. Taenia solium
C. Ancylostoma duodenale
D. Echinococcus granulosus
14. RA factor in Rheumatoid arthritis is a/an
A. Antigen
B. Auto-antibody
C. Hapten
D. Antibody
15. Graft between two individuals sharing same genetic constitution
is referred to as
A. Allograft
B. Isograft
C. Zenograft
D. Autograft
16. Which of these enzyme is not found inside the core of the virus
A. DNA Polymerase
B. Reverse transcriptase
C. Neuraminidase
D. RNA Polymerase
17. Amastigote forms of Leishmania donovani are found in
A. The cells of Reticuloedothelial system
B. Red blood cells
C. Culture media
D. Digestive tract of insect vector
18. RAST detects _______ hypersensitivity reaction
A. Type I
B. Type II
C. Type III
D. Type IV
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19. In PCR, denaturation occurs at
A. 55?C
B. 72?C
C. 95?C
D. None of the above
20. Which of these is not a live attenuated vaccine
A. TAB
B. MMR
C. Sabin's vaccine
D. BCG
SECTION 02
(General Microbiology, Immunology)
Q.2 Essay type question / clinical scenario based.
(12 marks)
Enlist & Describe in Detail about methods of gene transfer and discuss
the mechanisms of drug resistance in bacteria
Q.3 Short Note (any 4 out of 5)
(7X4=28 )
1. Mechanism of Bacterial Pathogenesis
2. Describe in detail the structure & Function of the Bacterial Cell wall
& write methods of Demonstration of cell wall.
3. Write in detail about Immune complex mediated hypersensitivity
reaction.
4. Classify immunity. Describe the various mechanism of
innate/acquired immunity.
5. Draw the two common complement activation pathways and
describe the importance of complement in health and disease.
SECTION 03
(Infections of Blood stream & Cardiovascular system, Gastro intestinal react &
Hepatobilliary system)
Q.4 Essay type question / clinical scenario based.
(12 marks)
Enumerate Hepatitis Viruses and their mode of transmission. Describe
viral markers, Treatment & Prophylaxis of Hepatitis B Infection.
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Q.5 Short Note (any 4 out of 5)
(7X4=28 )
1. A 35 year old male was admitted in causality with complain of
severe colicky abdominal pain. Patient gave H/O of stool passage
of blood and mucus with foul smell for last few days. Wet mount
stool preparation showed motile protozoa with pseudopodia. On
examination tenderness in right hypochondrium and mild
hepatomegaly is found.
a. What is the most probable cause for this condition?
(1 mark)
b. Write pathogenesis of this condition.
(3 marks)
c. Write the details of diagnostic modalities of above condition.
(3 marks)
2. A 25 year old man from urban area admitted in hospital presented
with high fever, headache, and retro orbital pain, sever back pain
for 5 days and bleeding nose today morning. On examination rash
are seen on the body. Blood reports shows platelet count is
20,000/mm3.
a. What is the most probable cause for this condition?
(1 mark)
b. Write pathogenesis of this condition.
(3 marks)
c. Write the details of laboratory diagnosis of above condition.
(3 marks)
3. Enumerate the nematodes infesting intestine. Describe the life
cycle, laboratory diagnosis of any one of them.
4. Classify Rickettsia. Describe the etiology, pathogenesis, laboratory
diagnosis of spotted fevers.
5. Rheumatic Fever
*****
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This post was last modified on 10 December 2024