Download VNSGU MBBS Second Year 2024 March-April 2106000102030102 S Microbiology Paper I Question Paper

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2106000102030102-S

EXAMINATION MARCH-APRIL 2024

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BACHELOR OF MEDICINE AND BACHELOR OF

SURGERY (SECOND YEAR)

MICROBIOLOGY (PAPER - II) (NEW) –

LEVEL 3 OMR

[Time: As Per Schedule]

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[Max. Marks: 100]

Instructions:

1. Fill up strictly the following details on your answer book
   1. Name of the Examination : BACHELOR OF MEDICINE AND BACHELOR OF SURGERY (SECOND YEAR)
   2. Name of the Subject : MICROBIOLOGY (PAPER - II) (NEW) - LEVEL 3 OMR
   3. Subject Code No : 2106000102030102-S

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2. Sketch neat and labelled diagram wherever necessary.
3. All questions are compulsory.
4. Draw a label Diagram wherever required with blue pen/pencil only
5. Write Heading of each question properly

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6. Write legibly

Section 01

Infections of skin soft tissues & musculoskeletal systems, Respiratory system, Infections of central nervous system, genitourinary system, Hospital acquired Infections, Miscellaneous

Q.1 MCQs 1×20=20

1. Aseptic meningitis is caused by
   1. Mumps Virus

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   2. H. influenza
   3. Meningococci
   4. Pneumococci
2. Scalded skin syndrome is mediated by:
   1. Hemolysin

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   2. Coagulase
   3. Entertoxin
   4. Epidermolytic toxin
3. Which of the following is true about Mycobacterium leprae?
   1. Acid fast bacilli

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   2. Also known as Hansen's bacilli
   3. Cannot be cultured on LJ medium
   4. All of the above
4. Histoplasma capsulatum is a:
   1. Yeast

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   2. Yeast like
   3. Mold
   4. Dimorphic fungi
5. Which of following is a gram negative coccobacillus which often shows bipolar staining?
   1. E.coli

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   2. Yersinia pestis
   3. Pseudomonas
   4. Vibrio cholera
6. Hand rub should not be used in which condition?
   1. Before touching a patient

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   2. After touching a patient
   3. After touching patient surrounding
   4. Hands are visibly soiled
7. Post exposure Prophylaxis is given for :
   1. Measles

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   2. Polio
   3. Rabies
   4. Tuberculosis
8. Holders method is heating at
   1. 65°C for 30 minutes

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   2. 63°C for 30 minutes
   3. 65°C for 20 minutes
   4. 63°C for 20 minutes
9. How much bacillary load in sputum is required for effective transmission of tuberculosis?
   1. 10 bacilli/ml

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   2. 100 bacilli/ml
   3. 1000 bacilli/ml
   4. 10000 bacilli/ml
10. TPHA stands for:
    1. T pallidum particle heat agglutination test

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    2. T pallidum haemagglutination assay test
    3. T pallidum hydro agglutination test
    4. None of above
11. Gumma is found in which stage of syphilis?
    1. Primary stage

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    2. Secondary stage
    3. Tertiary stage
    4. None
12. Infective form of Toxoplasma gondii is:
    1. Sporulated oocyst

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    2. Tissue cyst
    3. Pseudocyst
    4. All of the above
13. Mode of transmission of chlamydial conjunctivitis is:
    1. Direct contact with discharge

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    2. Contaminated clothes
    3. Flies
    4. All of the above
14. Carom coin appearance of colonies is seen in:
    1. S.pyogenes

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    2. S.agalactiae
    3. S.pneumoniae
    4. Viridans streptococci
15. Glass items should be segregated in which colour box?
    1. Yellow

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    2. Red
    3. Blue
    4. White
16. Production of early metachromatic granules can be seen best in which of the following media?
    1. Nutrient agar

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    2. Chocolate agar
    3. Loeffler's serum slope
    4. Potassium tellurite agar
17. Principle toxin responsible for gas gangrene is:
    1. Alpha

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    2. Theta
    3. Beta
    4. Delta
18. Generation time for Leprae bacilli is
    1. 15 to 20 seconds

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    2. 15 to 20 minutes
    3. 15 to 20 hours
    4. 12 to 13 days
19. Toxin production in Corynebacterium diphtheria is due to presence of
    1. beta phage

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    2. mutant gene
    3. plasmid
    4. transposome
20. Which of these parasite is an oriental lung fluke
    1. Fasiola hepatica

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    2. Fasiola buski
    3. Paragonimus wertermani
    4. Clonorchis sinensis

Section 02

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(Infections of skin soft tissues, musculoskeletal systems & Respiratory system)

Q.2 Essay type question / clinical scenario based. 12

A 52 year old man has been suffering from low grade evening rise fever, chronic cough, progressive weakness and weight loss about 15 kg since last 6 months. He is not responding to antibiotics prescribed by general practitioner.

1. What is your clinical diagnosis? 1
2. Write in detail about pathogenesis causative agent. 4

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3. Describe the Lab diagnosis of etiological agent in this patient. 5
4. Discuss types of resistance of this etiological agent. 2

Q.3 Short Note (any 4 out of 5) 7×4=28

1. Describe classification, complication & Laboratory Diagnosis of Leprosy
2. Describe the epidemiology, Pathogenesis & laboratory diagnosis of H1N1

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3. Describe Pathogenesis & laboratory diagnosis of Aspergillosis
4. Cutaneous Larva Migrans
5. Write about Laboratory Diagnosis, treatment & prophylaxis of Corynebacterium diphtheria.

Section 03

Infections of central nervous system, genitourinary system, Hospital acquired Infections, Miscellaneous

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Q.4 Essay type question / clinical scenario based. 12

A 20-year-old female patient visited the OPD with a four-day history of increased frequency of urination, dysuria, left flank pain and fever. On physical examination she had a temperature of 38.8°C and left costovertebral angle tenderness.

1. What is the most probable diagnosis? 1
2. What is the most common organism in such infection? 1
3. Describe the method sample collection, Transportation 2

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4. Describe Pathogenesis & laboratory test for diagnosis in such cases? 4+4

Q.5 Short Note (any 4 out of 5) 7×4=28

1. Enlist Viral agent causing Encephalitis. Describe pathogenesis & laboratory diagnosis of Rabies.
2. Define Sterilisation & Disinfection. Write in detail about stem sterilizer.
3. Describe Pathogenesis & laboratory diagnosis of Trichomonas vaginalis

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4. Congenital viral infections
5. Cryptococcal Meningitis