N-2006000102030002
Second Year M. B. B. S. Examination
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June / July - 2021
Pharmacology : Paper - II
Time : 2 Hours] [Total Marks : 40 Instructions : (1) ? ? - ? ? ? ? ? ?. Fillup strictly the details of signs on your answer book. Name of the Examination: Second Year M. B. B. S. Name of the Subject: Pharmacology : Paper - II Subject Code No.: Section No. (1, 2): 1&2 Student's Signature 2 0 0 6 0 0 0 1 0 2 0 3 0 0 0 2 SECTION - I Answer the following. 1×10=10 (a) Explain why a single dose of Penicillin G administered may prove fatal in some patients although it has high therapeutic index? (b) Name two antibiotics which can be safely used in hepatic failure. (c) Name one anabolic steroid and mention its therapeutic use. (d) Give two reasons for preferring Albendazole to Praziquantel in treatment of neurocysticercosis. (e) Why is ethambutol not used in children below six years? (f) Explain why local anesthetics occasionally fail to control pain sensation in inflamed tissue. (g) Explain why pentazocine is avoided in morphine addicts? (h) Mention two selective estrogen receptors modulators (SERM) with their therapeutic uses. (i) Name two antiviral agents used in the treatment of COVID 19 disease. (j) Explain the terms 'Antiseptic' and 'Disinfectant' with examples. N-2006000102030002] 1 [ Contd...
Answer any four of the following. 2×4=8 (a) Explain pharmacological basis of Disulfiram reaction and write name of two most common drugs causing it. (b) Enumerate two insulin analogues and mention their advantage over other type of insulins. (c) Describe concept of pre anesthetic medications with examples of at least two agents used for it. (d) Enumerate the adverse effects and contraindications of glucocorticoids. (e) Explain the pharmacological basis of use of Morphine in acute left ventricular failure. SECTION - II Answer any four of the following. 3×4=12 (a) Classify oral antidiabetic agents. Describe mechanism of action and adverse effects of Biguanides. (b) Enlist Fluroquinolones and describe mechanism of action and therapeutic uses of the same. (c) Classify various drugs for Parkinsonism. Give rational behind combining levodopa and benserzide. Mention various adverse effects observed during levodopa therapy. (d) Classify various anti-malarial drugs, write therapeutic uses and adverse effects of Chloroquine. (e) Enumerate various adverse effects of anti-cancer drug therapy in general and describe various strategies to prevent or decrease them. Answer any two of the following. 5×2=10 (a) Classify anti rheumatoid drugs. Describe mechanism of action, adverse effects and current clinical status of Disease Modifying antirheumatic drugs (DMARDs). (b) Classify antithyroid drugs. Describe the mechanism of action and adverse effects of (a) Carbimazole, (b) Radioactive Iodine. (c) Give various ways of classification of antimicrobial agents giving suitable examples. Describe various reasons leading to failure of chemotherapy. N-2006000102030002] 2 [ 120 ]--- Content provided by FirstRanker.com ---
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