Download JNTUK B.Pharm 2-1 2013 B2103 Physical Pharmaceutics Question Paper

Download JNTUK (Jawaharlal Nehru Technological University Kakinada / JNTU-Kakinada) B.Pharmacy (Bachelor of Pharmacy) 2-1 (2nd Year 1st Sem) 2013 April B2103 Physical Pharmaceutics Previous Question Paper

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Code No: B2103/R10 R10
II B.Pharmacy I Semester Supplementary Examinations, Apr/May 2013
PHYSICAL PHARMACEUTICS
Time: 3 hours Max Marks: 75
Answer any FIVE Questions
All Questions carry equal marks
?????
1. If 0.0160 g of oxygen dissolves in 1 litre of water at a temperature of 25
0
c and at
oxygen pressure of 300 mm Hg. Calculate a)  and b) the Bunsen coecient,  c)
How many grams of oxygen can be dissolved in 250 ml of aqueous solution when
the total pressure above the mixture is 760 mm Hg. The partial pressure of oxygen
in the solution is 0.263 atm and the temperature is 25
0
c. [15]
2. Write a note on
(a)Method of continuous variation
(b)pH Titration method. [8+7]
3. (a) The K value for the degradation reaction of a formulation at dierent tem-
perature are at 20
0
, 0.02 hr
1
and at 40
0
, 0.1254hr
1
. Calculate energy of
activation and Arrhenius factor.
(b) Give the equation and graphical representation of zero order, rst order and
second order of reaction? [8+7]
4. (a) How will you determine the surface tension by capillary rise method?
(b) What are the various factors that aect adsorption? State Freaundlich ad-
sorption isotherm and explain how would you verify it experimentally? [7+8]
5. (a) What is particle number? Derive an equation to determine particle number
of a powder using volume mean diameter.
(b) How is ow of powders important in manufacturing of tablets? What is the
problem we encounter in tablets manufacture with poor owing granules? How
do you overcome it? [7+8]
6. (a)Discuss the principle and working of cone and plate viscometer.
(b)Discuss the importance of rheology in pharmacy. [8+7]
7. Enumerate dierent types of colloids giving their salient features and examples.
[15]
8. Describe and explain the sedimentation parameters? How are they evaluated? [15]
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