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Code No: PHR16212
R16
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SET - 1
II B. Pharmacy I Semester Supplementary Examinations, May - 2019
PHARMACEUTICAL BIOCHEMISTRY
Time: 3 hours Max. Marks: 70
Note: 1. Question paper consists of two parts (Part-A and Part-B)
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2. Answering the question in Part-A is Compulsory
3. Answer any FOUR Questions from Part-B
PART-A
- a) Write functions of rough endoplasmic reticulum. (2M)
- b) What is the biological significance of potassium? (2M)
- c) What is insulin? (2M)
- d) What is the biological significance of bile salts? (2M)
- e) Why ATP is called a high energy compound? (2M)
- f) Why LDL is called bad cholesterol? (2M)
- g) What is protein turnover? (2M)
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PART -B
- a) Discuss the role of fatty acids in the functioning of cell membrane. (8M)
- b) Write in brief on carrier mediated transport mechanisms across cell membrane. (6M)
- a) Classify vitamins with examples. Write a note on significance of vitamin A. (9M)
- b) Write a note on chemical reactions of amino acids. (5M)
- a) With a neat sketch explain the biochemistry and significance of Krebs cycle. (8M)
- b) What is glycogenesis? Discuss its biological role. (6M)
- a) Outline the biosynthesis of cholesterol. Add a note on mechanisms involved in (10M) biological regulation of serum cholesterol.
- b) Write in brief on hormonal regulation of lipid metabolism. (4M)
- a) Discuss the ketabolic reactions of amino acids. (9M)
- b) Outline the metabolism of phenyl alanine. (5M)
- a) Classify enzymes with examples. Discuss the factors influencing activity of (10M) enzyme.
- b) Write short notes on coenzymes associated with oxidoreductase enzymes. (4M)
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