Q.P. Code: 105001
First Professional MBBS Degree Supplementary Examinations January 2019
Biochemistry - Paper I
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Time: 3 Hours Total Marks: 50
- Answer all questions
- Draw diagrams wherever necessary
Essay (10)
- Define gluconeogenesis. Describe how glucose is synthesized from alanine and add a note on its regulation. (2+6+2)
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Short essays (2x5=10)
- Classify carbohydrates with suitable examples. What are epimers.
- What are the functional and therapeutic role of prostaglandins.
Short notes (5x3=15)
- Formation and characters of peptide bond
- Essential amino acids.
- Competitive inhibition.
- Digestion of proteins
- Significance of 2,3 BPG
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Answer briefly (5x2=10)
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- What are the criteria to diagnose diabetes mellitus.
- What are exopeptidases and mention examples.
- Uncouplers of oxidative phosphorylation.
- Which is good cholesterol and why it is called so.
- Anaplerotic role of TCA cycle
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Give precise answers: (5x1=5)
- Enzyme defect in galactosemia.
- What is the clinical significance of transketolase.
- Which is the decarboxylation product of histidine.
- What are the amino acids that take part in the synthesis of carnitine.
- What is the function of lysosomes.
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