Download MBBS (Bachelor of Medicine, Bachelor of Surgery) KUHS (Kerala University of Health Science) 1st Year (First Year) 2022 Feb 2019 Scheme 115001 Biochemistry Paper I Previous Question Paper
2019 Scheme
Q.P. Code: 115001
Reg. no.: .....................
First Professional MBBS Degree Regular/Supplementary Examinations
February 2022
Biochemistry - Paper I
Time: 3 Hours
Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
? Indicate the question number correctly for the answer in the margin space
Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary
Long Essays
(2x15=30)
1. A 45-year-old bank manager visits the OPD with increased frequency of urination
(Polyuria), Increased thirst (Polydypsia) and increased hunger (Polyphagia). He also
gives the history of weight loss. On general examination, there were no significant
findings. The laboratory investigations were as follows:
Test
Result
Units
Biological Reference Interval
Random blood Glucose
316
mg/dl
70 - 140
Urine sugar
+ + + +
NIL
Answer the following questions using the above data:
What is the diagnosis.
Mention various methods for estimation of glucose
What are WHO criteria for diagnosis of this disorder
Why urine sugar was positive in this patient
Describe the various factors that regulate blood glucose level
(1+2+2+2+8)
2. Write IUMB classification of enzymes with examples and describe the factors affecting
the enzyme activity.
(7+8)
Short essays
(5x8=40)
3. Sources, RDA and biochemical functions of vitamin D
(2+1+5)
4. Describe the structural organization of proteins
(2+2+2+2)
5. Define obesity. What are the metabolic changes and complications of obesity (2+4+2)
6. Discuss the metabolism of chylomicrons
7. Classify phospholipids and enumerate their functions
(4+4)
Short answers
(5x4=20)
8. Ribosomes
9. Acute intermittent porphyria
10. Molecular basis and diagnosis of sickle cell anemia
11. Name the ketone bodies and describe their synthesis
12. Enumerate the clinical significance of HMP pathway
Give Precise Answers
(10x1=10)
13. Mention two high energy compounds
14. Mention two derivatives of cholesterol
15. What is HbA1c. What is its significance
16. Mention two sulphur containing amino acids
17. Give two examples for complete protein
18. Mention two lipotropic factors
19. Enzyme defect in galactosemia.
20. Name the semi essential amino acids.
21. Give biological reference range for serum triglycerides
22. Give biological reference range for serum albumin
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This post was last modified on 11 April 2022