Download MBBS KUHS 2nd Year 2021 December 201001 Pharmacology Paper I Previous Question Paper

Q.P. Code: 201001

Reg. No.: .........................

Second Professional MBBS Degree Supplementary Examinations

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December 2021

Pharmacology - Paper I

Time: 2 Hours

Max Marks: 40

• Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers

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• Indicate the question number correctly for the answer in the margin space
• Answer all parts of a single question together Leave sufficient space between answers
• Draw table/diagrams/flow charts wherever necessary

Essays: (2x6=12)

1. Classify antiepileptic drugs. Explain the mechanism of action, uses and adverse effects of phenytoin and sodium valproate. List four drugs used in status epilepticus.

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2. A 30 years old pregnant woman attended to hospital with a complaint of sudden onset of swelling of right leg and tenderness over calf. Venous Doppler of right leg suggestive of presence of a large thrombus in leg veins. (2+3+1)
   • Classify anticoagulants
   • Choose the ideal drug for this patient, write its mechanism of action and adverse effects.
   • What are advantages of low molecular weight heparins

Short Notes: (5x3=15)

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3. Plasma half life
4. Metoprolol
5. Neostigmine
6. Potassium sparing diuretics
7. Clinical uses of prostaglandins

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Write the Pharmacological basis for the use of: (3x1=3)

8. Pralidoxime in organophosphate compound poisoning
9. Carbidopa in combination with Levodopa.
10. Verapamil in paroxysmal supra ventricular tachycardia

Write two uses and two adverse effects of the following drugs: (3x1=3)

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11. Clonidine
12. Morphine
13. Ketamine

Choose the appropriate drug and Justify: (2x1=2)

14. Enalapril/amlodipine in hypertension with renal failure

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15. Dopamine/Dobutamine in congestive heart failure

Name the following (Two examples for each): (5x1=5)

16. Topical nasal decongestants
17. Atypical neuroleptics
18. Selective cyclooxygenase - 2 (COX-2) inhibitors

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19. Potassium channel openers
20. Anticholinergic bronchodilators

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