Rajiv Gandhi University of Health Sciences, Bangalore
I B.Pharm Degree Examination -
First Semester - May/June 2023
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[Time: 3 Hours] [Max. Marks: 75]
Modern Pharmaceutical Analytical Techniques
Q.P. CODE: 5101
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
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LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Define and derive Beer Lambert’s law. Add a note on its limitations.
- Explain the principle and instrumentation of NMR Spectroscopy.
- Enlist the different Ionisers used in MS and Explain any two in detail.
- Explain in detail Rate and Plate theory for Column efficiency. Add a note on applications of GC.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Discuss the Sample handling techniques used in IR Spectroscopy.
- What are Quenchers? Discuss the different types of quenching with examples.
- What is shielding and deshielding. Explain
- Discuss the principles of FT-NMR and 13C-NMR.
- Enlist the different peaks observed in MS and explain Isotopic peaks with examples.
- Write a note on HPTLC, and its applications.
- Explain the pumps and UV detectors used in HPLC.
- How are X-rays produced? What are modifications of X-ray tube?
- Explain the principle and working conditions of paper electrophoresis.
- Enlist the different electrodes used in potentiometry and explain the construction and working of any one electrode.
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