Rajiv Gandhi University of Health Sciences
Second Semester M. Pharmacy Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
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Modern Bio-Analytical Techniques - II
Q.P. CODE: 5150
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Describe in detail maintenance of records in BA/BE studies.
- Explain the principle and procedure involved in the solid phase Extraction of biological fluids.
- Describe agarose gel electrophoresis.
- Describe the good clinical practice guidelines.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- What are the facilities required to conduct BA/BE studies.
- What are the goals and objectives of GCP.
- Explain the merits and demerits of SPE.
- Write a note on SPE sorbents.
- Explain Protein precipitation.
- Briefly explain the factors affecting the separation of biomolecules by gel electrophoresis.
- Write the principle involved in the liquid extraction.
- Explain the sample collection methods for different biological systems.
- Explain briefly the documentation of GCP practice.
- Write a note on safety considerations in extracting from biological media.
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