Rajiv Gandhi University of Health Sciences
Second Semester M. Pharmacy Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
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Pharmaceutical Process Chemistry - II
Q.P. CODE: 5160
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Discuss the concept of validation of large scale process in detail.
- What are various fire hazards? Discuss various types of fire extinguishers.
- Explain aerobic fermentation? Write a note on production of vitamins.
- Discuss the various parameters of liquid equilibria. Write in detail about counter current extraction.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- Discuss the Scale up process of API with respect to case study.
- Define Filtration. Write a note on centrifugal filtration.
- What are the general methods available for preparation of polymorphs?
- Discuss various factors involved in moving from bench to pilot plant to full production.
- What are the various process equipment available for technical nitration.
- What are effluents? How are they managed in pharmaceutical industry?
- Write a note on catalytic halogenations.
- Explain various hydrogen transfer reaction by citing various examples.
- Discuss various types of oxidative reactions.
- Discuss types of halogenations. Write a note on industrial halogenations process.
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