Download RGUHS M.Pharm 2019 June 1st Year 5118 Advanced Organic Chemistry I Question Paper

First Semester M. Pharmacy Degree Examination

[Time: 3 Hours] [Max. Marks: 75]

Advanced Organic Chemistry - I

--- Content provided by‍ FirstRanker.com ---

Q.P. CODE: 5118

Your answers should be specific to the questions asked.

Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks

1. Explain mechanism, relative reactivity and orientation of SN1 and SN2 reactions.

--- Content provided by⁠ FirstRanker.com ---

2. Explain mechanism of Ullmann coupling and Sandmeyer reaction. Write their synthetic applications.
3. Explain synthesis of imidazole and pyrimidine. Write their applications.
4. Explain role of Functional Group Interconversion and Addition (FGI and FGA) in retrosynthesis with examples.

SHORT ESSAY (Answer any Nine) 5 X 9 = 45 Marks

1. Define carbocation. Explain its formation and stability. Write its synthetic application.

--- Content provided by‍ FirstRanker.com ---

2. Define carbanion. Explain its formation. Write its synthetic application.
3. Explain mechanism of Sandmeyer reaction.
4. Explain mechanism of Baeyer-Villiger oxidation.
5. Explain mechanism of protection of acetals and ketals.
6. Explain mechanism of protection of 1,2 and 1,3 diols.

--- Content provided by⁠ FirstRanker.com ---

7. Explain role of Wittig reagent in synthesis with suitable examples.
8. Explain synthesis of any one drug molecule containing quinoline nucleus.
9. Explain synthesis of pyrazole.
10. Explain strategies for synthesis of five membered rings with suitable examples.

FirstRanker.com

--- Content provided by‌ FirstRanker.com ---