Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 June (Master of Pharmacy) 1st Year (First Year) 1st Year 5118 Advanced Organic Chemistry I Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Semester M. Pharm Degree Examination - June-2019
[Time: 3 Hours]
[Max. Marks: 75]
Advanced Organic Chemistry ? I
Q.P. CODE: 5118
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Explain mechanism, relative reactivity and orientation of SN 1 and SN 2 reactions.
2.
Explain mechanism of ullman coupling and sandmeyer reaction. Write their synthetic
applications.
3.
Explain synthesis of imidazole and pyrimidine. Write their applications.
4.
Explain role of Functional Group Interconversion and Addition (FGI and FGA) in retrosynthesis
with examples.
SHORT ESSAY (Answer any Nine)
5 X 9 = 45 Marks
5.
Define carbocation. Explain its formation and stability. Write its synthetic application.
6.
Define carbanion. Explain its formation. Write its synthetic application.
7.
Explain mechanism of Sandmeyer reaction.
8.
Explain mechanism of Baeyer villager oxidation.
9.
Explain mechanism of protection of acetals and ketals.
10.
Explain mechanism of protection of f 1,2 and 1,3 diols.
11.
Explain role of wittig reagent in synthesis with suitable examples.
12.
Explain synthesis of any one drug molecule containing quinoline nucleus.
13.
Explain synthesis of pyrazole.
14.
Explain strategies for synthesis of five memered rings with suitable examples.
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