RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
Second Semester Examination
Biopharmaceutics and Pharmacokinetics
Q.P. CODE: 5167
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[Time: 3 Hours] [Max. Marks: 75]
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Describe phase II reactions with suitable examples.
- Explain factors affecting excretion.
- Describe the method of TDM for digoxin.
- Explain factors affecting drug distribution.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Explain the applications of biopharmaceutics and pharmacokinetics.
- Explain concept of drug clearance and give its significance.
- Dosage regimen (dose adjustment) in renal and hepatic failure
- Explain the significance of protein binding.
- Explain Blood Brain Barrier.
- General note on TDM
- Give MRT for various compartment models
- Explain the non renal excretion.
- Explain factors affecting excretion.
- Compare and contrast the non compartment model and physiological pharmacokinetic
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