Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 January (Master of Pharmacy) 1st Year (First Year) 1st Year 5101 Modern Pharmaceutical Analytical Techniques Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Semester M. Pharm Degree Examination - JAN-2019
[Time: 3 Hours]
[Max. Marks: 75]
Modern Pharmaceutical Analytical Techniques
Q.P. CODE: 5101
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Explain the instrumentation of double beam UV-Visible spectrophotometer with the help of a
neat diagram. Add a note on its advantages over single beam instrument.
2.
Discuss the Principle of NMR Spectroscopy. Explain chemical shift and the factors influencing
chemical shift.
3.
Explain the different parts of a Mass Spectrometer with the help of a neat diagram.
4.
Enlist the detectors used in Gas Chromatography and explain the construction & working of any
two detectors.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Explain the theory of fluorescence and factors affecting fluorescence.
6.
Discuss the modes of molecular vibrations that occur in IR region.
7.
Explain Spin-Spin Coupling constant.
8.
Write a note on 13C-NMR Spectroscopy.
9.
Explain briefly the Fragmentation rules used in MS.
10.
Write a note on Ion Exchange chromatography.
11.
Differentiate HPTLC from TLC.
12.
Explain the principles and working conditions of gel electrophoresis.
13.
Enlist the different X-ray diffraction techniques and explain any one in detail.
14.
Explain the principle and applications of ELISA
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