Download RGUHS M.Pharm 2019 Jan 1st Year 5101 Modern Pharmaceutical Analytical Techniques Question Paper

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Health Sciences

First Semester M. Pharmacy Degree Examination

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[Time: 3 Hours] [Max. Marks: 75]

Modern Pharmaceutical Analytical Techniques

Q.P. CODE: 5101

Your answers should be specific to the questions asked.

Draw neat, labeled diagrams wherever necessary.

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LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks

1. Explain the instrumentation of double beam UV-Visible spectrophotometer with the help of a neat diagram. Add a note on its advantages over single beam instrument.
2. Discuss the Principle of NMR Spectroscopy. Explain chemical shift and the factors influencing chemical shift.
3. Explain the different parts of a Mass Spectrometer with the help of a neat diagram.

4. Enlist the detectors used in Gas Chromatography and explain the construction & working of any two detectors.

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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks

1. Explain the theory of fluorescence and factors affecting fluorescence.
2. Discuss the modes of molecular vibrations that occur in IR region.
3. Explain Spin-Spin Coupling constant.
4. Write a note on ¹³C-NMR Spectroscopy.

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5. Explain briefly the Fragmentation rules used in MS.
6. Write a note on Ion Exchange chromatography.
7. Differentiate HPTLC from TLC.
8. Explain the principles and working conditions of gel electrophoresis.
9. Enlist the different X-ray diffraction techniques and explain any one in detail.

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10. Explain the principle and applications of ELISA

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