RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
First Semester M.Sc. Degree Examination
Health Sciences
[Time: 3 Hours] [Max. Marks: 75]
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Advanced Organic Chemistry -I
Q.P. CODE: 5118
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Discuss different methods applied for protecting and deprotecting (i) carbonyl (ii) carboxyl containing compound.
- Write the different strategies for synthesizing five and six membered heterocycles via retrosynthesis.
- Write the synthetic application of Ullmann coupling and Michael addition reaction.
- Explain SN1 and SN2 mechanism with suitable examples.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- Explain rearrangement reaction of carbocations with suitable example.
- Explain the role of triphenylphosphine in Wittig reaction.
- Write structure and uses of five medicinal compounds containing purine moiety.
- Write the guidelines for dissection of molecules.
- Give the synthetic applications of Imidazole and Quinoline moieties.
- Write the synthetic applications of Aluminium isopropoxide and N-bromosuccinimide.
- Explain the methods followed for C-C disconnection.
- Discuss in detail Mannich reaction.
- Write Sandmeyer's reaction and Ugi reaction.
- Write the synthetic application of Michael addition reaction.
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