Rajiv Gandhi University of Health Sciences
First Semester M. Pharmacy Degree Examination
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Time: Three Hours Max. Marks: 75 Marks
Advances Pharmaceutical Technology
Q.P. CODE: 5127
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
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LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Explain the techniques to study of crystal properties and thermal analysis in preformulation studies.
- Classify and discuss on biodegradable and natural polymers in drug formulations
- Write the layout and facility of cGMP process of LVP.
- Explain the compression process and force measurement in tablet manufacturing.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Describe in detail sterility testing of parenterals.
- Write the effect of surfactant, pH and cosolvents in drug solubilisation process.
- Explain briefly solid dispersions.
- Write a note on drug complexation technique in preformulation studies.
- Discuss about directly compressible vehicles in tablet formulations.
- Write short notes on hydrogels.
- Describe evaluation tests for small volume parenterals.
- Write the machinery involved in the filling of soft gelatin capsules.
- Write a note on importance of microscopic studies in preformulation.
- Explain the aqueous solubility, organic solubility and intrinsic solubility.
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