Download RGUHS M.Pharm 2019 Jan 1st Year Advanced Pharmacology And Toxicology Paper II Rs2 And Rs3 Question Paper

E!E{laaj?a? Eignejmv Isity of Health Sciences

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First Year M Pharm. Degree Examination - JAN. 2023

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[Time: 3 Hours] [Max. Marks: 100]

ADVANCED PHARMACOLOGY AND TOXICOLOGY

PAPER II

(RS2 & RS3)

Q.P. CODE : 9242

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Your answers should be specific to the questions asked.

Draw neat labeled diagrams wherever necessary.

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks

1. a. Define and Classify the receptors.
   b. Explain in detail G protein coupled receptors.
   

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   c. Write a note on drugs acting on GABA receptors.
2. a. Classify with examples antihypertensive drugs.
   b. Discuss the therapeutic role of calcium channel blockers.
   c. Discuss the role of local anesthetics in arrhythmia.
3. a. Immunomodulators
   

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   b. Discuss various in vivo and in vitro carcinogenicity studies.
   c. Explain the mechanism of multi drug resistance (MDR).

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks

4. Discuss the role of Nitric oxide as signaling molecule.
5. Write a note on bradykinin.

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6. Discuss about various insulin preparations.
7. Discuss Pharmacotherapy of Rheumatoid arthritis.
8. Discuss female reproductive toxicity.
9. Discuss chemoprophylaxis of tuberculosis

SHORT NOTES 2 X5 =10 Marks

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10. Oxygen free radicals
11. Mechanism of action of digitoxin

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