FirstRanker Logo

FirstRanker.com - FirstRanker's Choice is a hub of Question Papers & Study Materials for B-Tech, B.E, M-Tech, MCA, M.Sc, MBBS, BDS, MBA, B.Sc, Degree, B.Sc Nursing, B-Pharmacy, D-Pharmacy, MD, Medical, Dental, Engineering students. All services of FirstRanker.com are FREE

📱

Get the MBBS Question Bank Android App

Access previous years' papers, solved question papers, notes, and more on the go!

Install From Play Store

Download RGUHS M.Pharm 2019 Jan 2nd Year 5159 Computer Aided Drug Design Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 January (Master of Pharmacy) 1st Year (First Year) 2nd Year 5159 Computer Aided Drug Design Previous Question Paper

This post was last modified on 11 June 2021

This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences


E’E &Jaslgfi - a'fifig%niyegsig of Health §%i%§%es

Second Semester“m{“fi’fig?rtn fl"ekgré%OE‘xaminatlon

[Time: 3 Hours] [Max. Marks: 75]

--- Content provided by FirstRanker.com ---

Computer Aided Drug Design

Q.P. CODE: 5159

Your answers should be specific to the questions asked.

Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks

--- Content provided by FirstRanker.com ---

  1. Explain briefly different physiochemical properties used to determine the Quantitative structure activity relationship of drug molecules.
  2. Explain different energy minimization methods and compare global minimum conformation and bioactive conformation.
  3. Discuss the fragment based drug design and homology modeling.
  4. Explain the pharmacophore based and structure based In-silico virtual screening protocols.

SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks

--- Content provided by FirstRanker.com ---

  1. Explain in brief Hammett equation and sigma parameters.
  2. Enumerate the different methods in the calculation of partition co-efficient.
  3. Discuss the Free Wilson analysis and give its applications.
  4. What are the various statistical methods adopted for the QSAR analysis.
  5. Discuss the different approaches of 3D QSAR.
  6. --- Content provided by FirstRanker.com ---

  7. Discuss the agents used in the inhibition of HMG Co-A reductase enzyme.
  8. Discuss the different types of drug receptor interactions.
  9. Explain how ADMET properties are predicted for new molecules.
  10. Write a note on receptor/enzyme interaction and its analysis.
  11. How do you identify features of pharmacophore?
  12. --- Content provided by FirstRanker.com ---

FirstRanker.com



This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences

--- Content provided by FirstRanker.com ---