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University of Health Sciences
Second Semester M. Pharmacy Examination
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[Time: 3 Hours] [Max. Marks: 75]
Computer Aided Drug Delivery System -II
Q.P. CODE: 5171
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
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LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Give general overview of history of computers in pharmaceutical Research and development.
- What are the various computational techniques used in Absorption, Distribution and Excretion.
- Discuss computer aided formulation development of microemulsion with example.
- What is Artificial Intelligence? Give its pharmaceutical application along with Advantages and Disadvantages.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Explain ICH Q8 guidelines.
- Explain about population modeling.
- Write about Organic Anionic Transporter (OATP) used in computational modeling.
- Discuss about clinical Data collection.
- Write a note on the concept of optimization.
- Write about factorial design used in optimization.
- Describe the computer simulation using isolated tissue or organism.
- What is virtual trial in computer aided GI simulation.
- Discuss the role of CFD (Computational Fluid Dynamics) in Pharma industry.
- How is robotics and pharmaceutical automation influencing Pharma industry.
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