First Year M. Pharm Degree Examination FirstRanker.com
[Time: 3 Hours] [Max. Marks: 100]
MODERN PHARMACEUTICAL ANALYSIS
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(RS2 & RS3)
Q.P. CODE: 9201
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
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- Define Beer’s-Lambert’s law. Add a note on limitations of beers law. Explain in detail instrumentation of UV-Visible spectrophotometer.
- Explain the principle involved in chemical ionization, FAB and Field ionization techniques. Write its merit and demerits. Explain the working of Quadrupole and Ion-trap mass analyser
- Explain about the different derivatizations and detectors used in Gas Chromatography.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- What are the different vibrational modes of polyatomic molecules upon IR absorption? Write in brief on the various detectors used in IR Spectroscopy.
- Explain the cotton effect curve. Explain in brief of octant rule and its applications.
- Explain different regions in IR Spectroscopy and also discuss about detectors used.
- What is chemical shift? Explain with examples different factors influencing chemical shift.
- Write the principle involved in paper chromatography. Explain the various methods of preparation of TLC plates.
- Define Electrophoresis. Write the principle of Electrophoresis for separation of molecular mixture.
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SHORT NOTES 2 X5 = 10 Marks
- Write the applications of x-ray diffraction methods:
- Explain briefly about the importance of statistical-analysis.
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