Rajiv Gandhi University of Health Sciences
First Year M Pharm Degree Examination - January 2018
[Time: 3 Hours] [Max. Marks: 100]
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Advances in Drug Delivery Systems
(Revised Scheme 4)
Q.P. CODE: 9339
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.
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LONG ESSAY (Answer any TEN) 10 X 10 = 100 Marks
- Explain the reservoir type diffusion controlled drug delivery system with example. Discuss the evaluation of controlled drug delivery system.
- Illustrate the mechanism of biodegradation of polymers with examples.
- Discuss the effect of crystallinity of polymers and effect of fillers on the controlled drug delivery systems.
- Explain the feedback controlled drug delivery system with examples.
- Discuss rectal mucoadhesive drug delivery systems with examples.
- Discuss the diagnostic applications of monoclonal antibodies with respect to auto immune diseases. Explain inverse and dual targeting of drugs.
- Discuss the evaluation parameters of transdermal systems.
- Discuss the formulation of long acting insulin parenteral controlled release preparations.
- Discuss the formulation, evaluation and applications of solid lipid nanoparticles.
- Mention the different types of vesicular drug delivery systems. Give the general method of preparation and applications of virosomes.
- Explain the formulation and evaluation of metal nanoparticles.
- Explain in detail formulation and evaluation of niosomes.
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