First Year M Pharm Degree Examination
[Time: 3 Hours] [Max. Marks: 100]
Molecular Biology
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(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.
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LONG ESSAY (Answer any TEN) 10 X 10 = 100 Marks
- Explain the signalling pathways involving cAMP and PI3 kinase and write their significance in metabolism.
- What is animal cell culture? Discuss the basic requirement, techniques and applications of animal cell culture.
- Explain the mechanism of excitation and contraction with example.
- Write any four differences between embryonic stem cells and adult stem cells. What is somatic cell nuclear transfer and its application.
- Explain the basic technique and applications of microarray.
- Write short notes on restriction digestion enzymes and cloning vectors.
- What is sense and antisense technology? Mention four application of antisense technology.
- Explain the principle and four applications of gene therapy.
- Write the principles and applications of MTT and COMET.
- Discuss about glycobiology and catalytic antibodies.
- Explain the process of polymerase chain reaction and list its applications.
- Explain the salient features of human genome project.
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