Rajiv Gandhi University of Health Sciences
First Year M Pharm Degree Examination - January 2011
[Time: 3 Hours] [Max. Marks: 100]
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Chemical and Biological Evaluation
(Revised Scheme 4)
Q.P. CODE: 9360
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary. Answer any ten questions.
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LONG ESSAY (Answer any TEN) 10 X 10 = 100 Marks
- Explain the process of salvaging of returned goods and WHO certification for export of pharmaceuticals.
- Draw a neat outline of QC lab and explain in detail its planning, design and layout.
- Explain in detail the methodology and interpretation of Bacterial Enumeration Test (BET).
- Explain the various applications, advantages and disadvantages of computers in quality control laboratory.
- Give an elaborate note on calibration procedure of UV - Visible spectrophotometer and analytical balance.
- What is technology transfer and method verification?
- Explain chemical and bacteriological analysis of purified water and potable water.
- Define bioassay. Explain the principle and procedure for the bioassay of Streptokinase.
- Explain the principle, methodology involved in microbiological assay of antibiotics by turbidimetric method.
- Mention the various parameters for stability studies and impurity profiling of Q3A and Q3B.
- Explain the methodology of microbiological assay of antibiotics.
- Write a note on sample preparation of biological samples.
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