Second Semester M. Pharm Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
Advanced Biopharmaceutics and Pharmacokinetics -II
--- Content provided by FirstRanker.com ---
Q.P. CODE: 5141
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Explain the factors influencing GI absorption of a drug from its dosage form.
- What is compartment model? Describe how can calculate the absorption rate constant following oral administration of a drug confers one compartment characteristics in the body.
- Explain the problems of variable controls in dissolution testing of dosage forms.
- Define bioavailability? Discuss the methods available to enhance bioavailability.
--- Content provided by FirstRanker.com ---
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Write briefly on Michaelis-Menten equation.
- Discuss on kinetics of protein binding.
- Describe Noyes-Whitney dissolution rate law.
- Define bioequivalence? Explain its clinical significance.
- Elaborate the relationship between pharmacokinetics and pharmacodynamics.
- Discuss various approaches for improving solubility of poorly soluble drugs.
- Explain in brief concept of targeted drug delivery systems.
- Discuss in vitro-in vivo correlation.
- Write a note on biopharmaceutical classification system.
- Explain in brief multi compartment model.
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
--- Content provided by FirstRanker.com ---