RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
Second Semester Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
Advanced Organic Chemistry-II
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Q.P. CODE: 5158
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- What is green chemistry? Discuss the principle and applications of green chemistry.
- Explain strategies for solution phase peptide synthesis.
- With help of correlation diagram, show that cyclisation of hexatriene to cyclohexadiene on heating proceeds by disrotatory mode.
- Write about Chan, Ingold and Prelog (CIP) sequence rule.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Write the principle and advantages of continuous flow reactors.
- Write a note on liquid-solid reaction and synthetic application.
- Write note on solid phase peptide synthesis.
- Explain in details about various solid supports and linkers.
- Explain FMO method for analyzing an electrocyclic reaction by taking one example.
- Advantages and disadvantages of catalysis
- Write a note on regeneration of heterogenous catalysts.
- Use of enzymes in organic synthesis
- Explain about the chiral pool and the asymmetric drug synthesis techniques.
- Discuss any three methods for resolution of racemic compounds.
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