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Download RGUHS M.Pharm 2018 May 2nd Year 5159 Computer Aided Drug Design II Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2018 May (Master of Pharmacy) 2nd Year 5159 Computer Aided Drug Design II Previous Question Paper

This post was last modified on 11 June 2021

This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences


Second Semester Pharm. Degree Examination

[Time: 3 Hours] [Max. Marks: 75]

Computer Aided Drug Design -II

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Q.P. CODE: 5159

Your answers should be specific to the questions asked.

Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks

  1. Explain Hansch and Free Wilson method of analysis with a suitable example and relationship between them.
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  3. Discuss the approaches for 3D-QSAR analysis.
  4. Write the protocols to be followed in In silico virtual screening.
  5. Discuss the energy minimization methods in molecular modeling.

SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks

  1. Describe the docking of agents on AchE.
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  3. Explain the method of generation of 3D-structure of a protein.
  4. What is log P? How it is determined? Give its significance.
  5. Explain the docking of agents on DHFR enzyme.
  6. Explain pharmacophore mapping.
  7. Discuss homology modeling of a protein.
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  9. Describe extra precision docking.
  10. Explain the electronic parameters to be considered in QSAR.
  11. Write a note on counter map analysis.
  12. Discuss the role of computer aided drug design in drug discovery.

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This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences

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