This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
Second Semester Pharm. Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
Computer Aided Drug Design -II
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Q.P. CODE: 5159
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
- Explain Hansch and Free Wilson method of analysis with a suitable example and relationship between them.
- Discuss the approaches for 3D-QSAR analysis.
- Write the protocols to be followed in In silico virtual screening.
- Discuss the energy minimization methods in molecular modeling.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Describe the docking of agents on AchE.
- Explain the method of generation of 3D-structure of a protein.
- What is log P? How it is determined? Give its significance.
- Explain the docking of agents on DHFR enzyme.
- Explain pharmacophore mapping.
- Discuss homology modeling of a protein.
- Describe extra precision docking.
- Explain the electronic parameters to be considered in QSAR.
- Write a note on counter map analysis.
- Discuss the role of computer aided drug design in drug discovery.
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This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
--- Content provided by FirstRanker.com ---