Rajiv Gandhi University of Health Sciences
Second Semester B.Pharm Degree Examination
[Time: 3 Hours] [Max. Marks: 75]
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Biopharmaceutics and Pharmacokinetics
Q.P. CODE: 5167
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Describe Phase I reactions of oxidation with suitable examples.
- Explain factors affecting protein binding.
- Explain the dosage regimen.
- Explain physiological pharmacokinetic model with advantages and disadvantages.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- Loading dose and maintenance dose
- Explain concept of drug clearance and give its significance.
- Dosage regimen (Dose adjustment) in renal and hepatic failure
- Explain non-compartment pharmacokinetic model.
- List out all factors and explain factors (any six) affecting biotransformation.
- Define volume of distribution and explain the significance of it.
- Explain the statistical moment theory.
- Explain the displacement interactions with significance.
- Explain the accumulation index and its importance.
- Explain individualization of therapy.
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This download link is referred from the post: RGUHS M.Pharm 2nd Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
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