Rajiv Gandhi University of Health Sciences
Degree Examination - First Semester
[Time: 3 Hours] [Max. Marks: 75]
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Phytochemistry
Q.P. CODE: 5132
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- Explain the various methods of extractions with emphasis on choice of solvents.
- Explain the biosynthesis, isolation and characterization of strychnine and digitoxin.
- Explain selection and optimization of lead compounds with respect to anticancer and antitubercular drugs.
- Explain the different methods of screening of antiurolithiatic and analgesic activity.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- Write the biosynthetic pathway of ephedrine.
- Explain different methods of fractionation of extracts.
- Explain the difference between the preparative HPLC and Flash chromatography.
- Write the method of isolation, purification and characterization of withanolides.
- Describe HPTLC fingerprinting of drugs containing alkaloids.
- Explain LCMS analysis of saponins.
- Explain protocol design for lead molecules from plants with examples.
- List out various Invitro Invivo methods of antipsychotic Phytoconstituents and explain any one Invivo method
- Explain the techniques of AAS (Atomic Absorption Spectroscopy) in analysis of herbal drugs.
- Explain SCFE technique with advantages and disadvantages.
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