RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
First Semester Degree Examinations
[Time: 3 Hours] [Max. Marks: 75]
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Pharmacological and Toxicological Screening Methods-I
Q.P. CODE: 5135
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three) 3 X 10 = 30 Marks
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- What are various animal models for evaluation of antiulcer drugs? Write any two preclinical models for screening of anti-parkinsonism drugs.
- Explain the three preclinical screening models for anti-epileptics
- Explain the three preclinical screening models for anti-hypertensive agents
- Explain the three methods of evaluating anti-cancer drugs.
SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
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- What are the applications of transgenic animals in research?
- What are the breeding techniques of laboratory animals?
- Explain the principle and method of MTT assay.
- Write any two preclinical evaluation method for Immunosuppressant
- Explain any two pharmacology screening method for anti-diabetic agents.
- List out the methods for screening of antidiarrhoeal activity and explain any one of them
- Enumerate the in-vitro and in-vivo animal model for screening of anti-inflammatory agents.
- Enlist the in vivo preclinical model for anti-dyslipidemic agents. Explain any one in vitro model for screening of anti-dyslipidemic agents.
- How do you conduct the immunoassay of insulin and digoxin?
- How do you differentiate the heterogeneous and homogenous immunoassay systems?
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