Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2016 November (Master of Pharmacy) 1st Year 9283 Biopharmaceutics And Pharmacokinetics Rs 2 And Rs 3 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - NOV 2016
[Time: 3 Hours]
[Max. Marks: 100]
BIOPHARMACEUTICS AND PHARMACOKINETICS
(RS 2 & RS 3)
Q.P. CODE : 9283
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Classify and explain dosage form related factors affecting drug absorption.
2.
Write a note on Phase I reactions of biotransformation.
3.
Deduce equations to obtain pharmacokinetic parameters of a drug administered by oral route,
the drug undergoing absorption by first order kinetics and body acting as a single
compartment.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
What are the causes of non-linearity?
5.
What are in-vitro and in-vivo methods of determining absorption?
6.
Write a note on measurement of bioavailability.
7.
Explain factors affecting excretion of drugs.
8.
Explain the basic concept of Therapeutic Drug Monitoring.
9.
Explain pH partition hypothesis.
SHORT NOTES
2 X 5 = 10 Marks
10.
Discuss induction of drug metabolizing enzymes.
11.
How are ionic/ionizable drugs absorbed?
* * * * *

---

Document Outline

• ??
• ??
• ??
• ??

---